Bioinformatics and Computational Biology

• BIOINFORMATICS ANALYSIS SERVICE
• Amplicon analysis (16S rRNA)

• Quality control.
• Alpha and beta diversity analysis.
• Taxonomic analysis (OTU abundance).
• Association analysis between condition/treatment and OTU abundance.
• OTU differential abundance analysis.

• De novo sequencing of small genomes (Prokaryotes-Levittas).

• Data preprocessing and quality analysis.
• Genome assembly.
• Gene annotation and functional identification.
• Variant identification, filtering and annotation.
• Comparative genomics:
• Pangenome analysis.
• Global genomic alignment between samples.
• Genotype-phenotype association analysis.
• Impact of presence/absence of genes on phenotype.
• Impact of variants on phenotype.

• Genomic resequencing (exomes, whole genome and panels).

• Data preprocessing and quality analysis.
• Mapping of reads to reference genome.
• Variant identification, filtering and annotation.

• Expression analysis (RNA-Seq / Microarrays).

• Public data access and analysis (e.g. GEO, ArrayExpress, SRA).
• Data preprocessing and quality analysis.
• Differential expression analysis.
• miRNA target gene prediction.
• Functional enrichment analysis: metabolic pathway (KEGG, Reactome and WikiPathways) and Gene Ontology.

• Survival analysis.

• Univariate and multivariate Cox regression analysis.
• Kaplan-Meier curves.
• Gene signature search.

• HIGH PERFORMANCE COMPUTING SERVICE



We provide the necessary resources for intensive computation in the computational cluster, as well as update policies and distribution of computational resources.