Oncohematología y Genética

Terapia celular y nuevas dianas terapéuticas en onco-hematología

2020
Revista Internacional

A Randomized, Double-Blind, Placebo-Controlled Trial (TAURCAT Study) of Citrate Lock Solution for Prevention of Endoluminal Central Venous Catheter Infection in Neutropenic Hematological Patients

Gudiol, C; Arnan, M; Aguilar-Guisado, M; Royo-Cebrecos, C; Sanchez-Ortega, I; Montero, I; Martin-Gandul, C; Laporte-Amargis, J; Albasanz-Puig, A; Nicolae, S; Perayre, M; Berbel, D; Tebe, C; Riera, J; Sureda, A; Cisneros, JM; Carratala, J

Vol: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Revista Internacional
Revista Internacional

A pediatric regimen for adolescents and young adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: Results of the ALLRE08 PETHEMA trial

Ribera, JM; Morgades, M; Montesinos, P; Tormo, M; Martinez-Carballeira, D; Gonzalez-Campos, J; Gil, C; Barba, P; Garcia-Boyero, R; Coll, R; Pedreno, M; Ribera, J; Mercadal, S; Vives, S; Novo, A; Genesca, E; Hernandez-Rivas, JM; Bergua, J; Amigo, ML; Vall-Llovera, F; Martinez-Sanchez, P; Calbacho, M; Garcia-Cadenas, I; Garcia-Guinon, A; Sanchez-Sanchez, MJ; Cervera, M; Feliu, E; Orfao, A

Vol: CANCER MEDICINE Revista Internacional
Revista Internacional

ASXL1 mutation as a surrogate marker in acute myeloid leukemia with myelodysplasia-related changes and normal karyotype

Prats-Martin, C; Burillo-Sanz, S; Morales-Camacho, RM; Perez-Lopez, O; Suito, M; Vargas, MT; Caballero-Velazquez, T; Carrillo-Cruz, E; Gonzalez, J; Bernal, R; Perez-Simon, JA

Vol: CANCER MEDICINE Revista Internacional
Revista Internacional

Blinatumomab and inotuzumab for B cell precursor acute lymphoblastic leukaemia in children: a retrospective study from the Leukemia Working Group of the Spanish Society of Pediatric Hematology and Oncology (SEHOP)

Fuster, JL; Molinos-Quintana, A; Fuentes, C; Fernandez, JM; Velasco, P; Pascual, T; Rives, S; Dapena, JL; Sisinni, L; Lopez-Godino, O; Palomo, P; Villa-Alcazar, M; Bautista, F; Gonzalez-Vicent, M; Lopez-Duarte, M; Garcia-Morin, M; Ramos-Elbal, E; Ramirez, M

Vol: BRITISH JOURNAL OF HAEMATOLOGY Revista Internacional
Revista Internacional

Characteristics and outcome of adult patients with acute promyelocytic leukemia and increased body mass index treated with the PETHEMA Protocols

Sobas, M; Rodriguez-Veiga, R; Vellenga, E; Paluszewska, M; De la Serna, J; Garcia-Alvarez, F; Gil, C; Brunet, S; Bergua, J; Gonzalez-Campos, J; Ribera, JM; Tormo, M; Gonzalez, M; Fernandez, I; Benavente, C; Gonzalez-Sanmiguel, JD; Esteve, J; Perez-Encinas, M; Salamero, O; Manso, F; Lowenberg, B; Sanz, MA; Montesinos, P

Vol: EUROPEAN JOURNAL OF HAEMATOLOGY Revista Internacional
Revista Internacional

Circulating microRNA after autologous bone marrow mononuclear cell (BM-MNC) injection in patients with ischemic stroke

Mancha, F; Escudero-Martinez, I; Zapata-Arriaza, E; Vega-Salvatierra, A; Cabezas, JA; Lebrato, L; Pardo, B; De-La-Torre, J; Zapata, M; Escamilla, V; Calderon-Cabrera, C; Martin-Sanchez, J; Valverde, R; Aguera-Morales, E; Herrera, I; Delgado, F; Gamero, MA; Perez-Sanchez, S; Moya, M; Espinosa, R; Ortega-Quintanilla, J; Gutierrez-Jarrin, I; Gonzalez-Garcia, A; Montaner, J; Moniche, F

Vol: JOURNAL OF INVESTIGATIVE MEDICINE Revista Internacional
Revista Internacional

Conditioning-based outcomes after allogeneic transplantation for myeloma following a prior autologous transplant (1991-2012) on behalf of EBMT CMWP

Hayden, PJ; Iacobelli, S; Perez-Simon, JA; van Biezen, A; Minnema, M; Niittyvuopio, R; Schonland, S; Meijer, E; Blaise, D; Milpied, N; Marquez-Malaver, FJ; Veelken, JH; Maertens, J; Michallet, M; Cammenga, J; N'Guyen, S; Niederwieser, D; Hunault-Berger, M; Bourhis, JH; Passweg, J; Bermudez, A; Chalandon, Y; Yakoub-Agha, I; Garderet, L; Kroger, N

Vol: EUROPEAN JOURNAL OF HAEMATOLOGY Revista Internacional
Revista Internacional

Critical role of PD-L1 expression on non-tumor cells rather than on tumor cells for effective anti-PD-L1 immunotherapy in a transplantable mouse hematopoietic tumor model

Rodriguez-Barbosa, JI; Azuma, M; Zelinskyy, G; Perez-Simon, JA; del Rio, ML

Vol: CANCER IMMUNOLOGY IMMUNOTHERAPY Revista Internacional
Revista Internacional

Differential biomarker profiles between unprovoked venous thromboembolism and cancer

Sanchez-Lopez, V; Gao, L; Ferrer-Galvan, M; Arellano-Orden, E; Elias-Hernandez, T; Jara-Palomares, L; Asensio-Cruz, MI; Castro-Perez, MJ; Rodriguez-Martorell, FJ; Lobo-Beristain, JL; Ballaz-Quincoces, A; Lopez-Campos, JL; Vila-Liante, V; Otero-Candelera, R

Vol: ANNALS OF MEDICINE Revista Internacional
Revista Internacional

Efficacy of bortezomib to intensify the conditioning regimen and the graft-versus-host disease prophylaxis for high-risk myeloma patients undergoing transplantation

Caballero-Velazquez, T; Calderon-Cabrera, C; Lopez-Corral, L; Puig, N; Marquez-Malaver, F; Perez-Lopez, E; Garcia-Calderon, C; Rosso-Fernandez, CM; Barrigon, DC; Martin, J; Mateos, MV; San Miguel, J; Perez-Simon, JA

Vol: BONE MARROW TRANSPLANTATION Revista Internacional
Revista Internacional

Evolving treatment patterns and outcomes in older patients (>= 60 years) with AML: changing everything to change nothing?

Martinez-Cuadron, D; Serrano, J; Gil, C; Tormo, M; Martinez-Sanchez, P; Perez-Simon, JA; Garcia-Boyero, R; Rodriguez-Medina, C; Lopez-Pavia, M; Benavente, C; Bergua, J; Lavilla-Rubira, E; Amigo, ML; Herrera, P; Alonso-Dominguez, JM; Bernal, T; Colorado, M; Sayas, MJ; Algarra, L; Vidriales, MB; Rodriguez-Macias, G; Vives, S; Perez-Encinas, MM; Lopez, A; Noriega, V; Garcia-Fortes, M; Ramos, F; Rodriguez-Gutierrez, JI; Costilla-Barriga, L; Labrador, J; Boluda, B; Rodriguez-Veiga, R; Martinez-Lopez, J; Sanz, MA; Montesinos, P

Vol: LEUKEMIA Revista Internacional
Revista Internacional

Filanesib in combination with pomalidomide and dexamethasone in refractory MM patients: safety and efficacy, and association with alpha 1-acid glycoprotein (AAG) levels. Phase Ib/II Pomdefil clinical trial conducted by the Spanish MM group

Ocio, EM; Motllo, C; Rodriguez-Otero, P; Martinez-Lopez, J; Cejalvo, MJ; Martin-Sanchez, J; Blad, J; Garcia-Malo, MD; Dourdil, MV; Garcia-Mateo, A; de Arriba, F; Garcia-Sanz, R; de la Rubia, J; Oriol, A; Lahuerta, JJ; San-Miguel, JF; Mateos, MV

Vol: BRITISH JOURNAL OF HAEMATOLOGY Revista Internacional
Revista Internacional

Graft-versus-host disease prophylaxis: Pathophysiology-based review on current approaches and future directions

Martinez-Cibrian N; Zeiser R; Perez-Simon JA

Vol: Blood reviews Revista Internacional
Revista Internacional

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Perez, C; Botta, C; Zabaleta, A; Puig, N; Cedena, MT; Goicoechea, I; Alameda, D; San Jose-Eneriz, E; Merino, J; Rodriguez-Otero, P; Maia, C; Alignani, D; Maiso, P; Manrique, I; Lara-Astiaso, D; Vilas-Zornoza, A; Sarvide, S; Riillo, C; Rossi, M; Rosinol, L; Oriol, A; Blanchard, MJ; Rios, R; Sureda, A; Martin, J; Martinez, R; Bargay, J; de la Rubia, J; Hernandez, MT; Martinez-Lopez, J; Orfao, A; Agirre, X; Prosper, F; Mateos, MV; Lahuerta, JJ; Blade, J; San-Miguel, JF; Paiva, B

Vol: BLOOD Revista Internacional
Revista Internacional

Long-term survival of 1338 MM patients treated with tandem autologous vs. autologous-allogeneic transplantation

Costa, LJ; Iacobelli, S; Pasquini, MC; Modi, R; Giaccone, L; Blade, J; Schonland, S; Evangelista, A; Perez-Simon, JA; Hari, P; Brown, EE; Giralt, SA; Patriarca, F; Stadtmauer, EA; Rosinol, L; Krishnan, AY; Gahrton, G; Bruno, B

Vol: BONE MARROW TRANSPLANTATION Revista Internacional
Revista Internacional

Measurable Residual Disease by Next-Generation Flow Cytometry in Multiple Myeloma

Paiva, B; Puig, N; Cedena, MT; Rosinol, L; Cordon, L; Vidriales, MB; Burgos, L; Flores-Montero, J; Sanoja-Flores, L; Lopez-Anglada, L; Maldonado, R; de la Cruz, J; Gutierrez, NC; Calasanz, MJ; Martin-Ramos, ML; Garcia-Sanz, R; Martinez-Lopez, J; Oriol, A; Blanchard, MJ; Rios, R; Martin, J; Martinez-Martinez, R; Sureda, A; Hernandez, MT; de la Rubia, J; Krsnik, I; Moraleda, JM; Palomera, L; Bargay, J; Van Dongen, JJM; Orfao, A; Mateos, MV; Blade, J; San-Miguel, JF; Lahuerta, JJ

Vol: JOURNAL OF CLINICAL ONCOLOGY Revista Internacional
Revista Internacional

Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material

Lebron, JA; Ostos, FJ; Lopez-Lopez, M; Moya, ML; Sales, C; Garcia, E; Garcia-Calderon, CB; Garcia-Calderon, M; Pena-Gomez, MJ; Rosado, IV; Balestra, FR; Huertas, P; Lopez-Cornejo, P

Vol: PHARMACEUTICS Revista Internacional
Revista Internacional

Overcoming Chimeric Antigen Receptor (CAR) Modified T-Cell Therapy Limitations in Multiple Myeloma

Garcia-Guerrero, E; Sierro-Martinez, B; Perez-Simon, JA

Vol: FRONTIERS IN IMMUNOLOGY Revista Internacional
Revista Internacional

Pembrolizumab as Consolidation Strategy in Patients with Multiple Myeloma: Results of the GEM-Pembresid Clinical Trial

Puig, N; Corchete-Sanchez, LA; Perez-Moran, JJ; Davila, J; Paino, T; de la Rubia, J; Oriol, A; Martin-Sanchez, J; de Arriba, F; Blad, J; Blanchard, MJ; Gonzalez-Calle, V; Garcia-Sanz, R; Paiva, B; Lahuerta, JJ; San-Miguel, JF; Mateos, MV; Ocio, EM

Vol: CANCERS Revista Internacional
Revista Internacional

Performance of prognostic scoring systems in elderly patients with acute myeloid leukaemia on intensive chemotherapy: A PETHEMA registry study

Rodriguez-Medina, C; Martinez-Cuadron, D; Cano, I; Gil, C; Tormo, M; Martinez-Sanchez, MD; del Castillo, TB; Serrano-Lopez, J; Benavente, C; Herrera-Puente, P; Garcia-Boyero, R; Lavilla-Rubira, E; Amigo, ML; Sayas-Llorisn, MJ; Bergua-Burgues, JM; Perez-Simon, JA; Rodriguez, G; Espadana, A; Vidriales-Vicente, B; Fernandez, R; Lopez-Lorenzo, JL; Lopez, M; Garcia-Fortes, M; Gomez, JL; Colorado-Araujo, M; Sossa-Melo, CL; Aguilar, E; Fernandez, PM

Vol: LEUKEMIA RESEARCH Revista Internacional
Revista Internacional

Polyphenolic Extract (PE) from Olive Oil Exerts a Potent Immunomodulatory Effect and Prevents Graft-versus-Host Disease in a Mouse Model

Alvarez-Laderas, I; Ramos, TL; Medrano, M; Caracuel-Garcia, R; Barbado, MV; Sanchez-Hidalgo, M; Zamora, R; Alarcon-de-la-Lastra, C; Hidalgo, FJ; Piruat, JI; Caballero-Velazquez, T; Perez-Simon, JA

Vol: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION Revista Internacional
Revista Internacional

Retrieval of germinal zone neural stem cells from the cerebrospinal fluid of premature infants with intraventricular hemorrhage

Fernandez-Munoz, B; Rosell-Valle, C; Ferrari, D; Alba-Annador, J; Montiel, MA; Campos-Cuerva, R; Lopez-Navas, L; Munoz-Escalona, M; Martin-Lopez, M; Profico, DC; Blanco, MF; Giorgetti, A; Gonzalez-Munoz, E; Marquez-Rivas, J; Sanchez-Pernaute, R

Vol: STEM CELLS TRANSLATIONAL MEDICINE Revista Internacional
Revista Internacional

Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study

Gomez, VE; Garcia-Gutierrez, V; Corral, LL; Cadenas, IG; Martinez, AP; Malaver, FMJ; Caballero-Velazquez, T; Sierra, PGA; Alegria, MCV; Salinas, IPM; Cabrera, CC; Vicent, MG; Torres, NR; Porras, RP; Coll, CF; Orti, G; Ferreiras, DV; Llanza, RD; Moles, P; Velazquez-Kennedy, K; Mende, MJ; Barrigon, DC; Perez, E; Bofarull, RM; Gerosa, SS; Sierra, J; Poch, M; Ripa, MTZ; Perez, MDA; Angulo, BM; Ortega, IS; Caballer, JS; Gomez, JM; Tocino, IE; Perez-Simon, JA

Vol: BONE MARROW TRANSPLANTATION Revista Internacional
Revista Internacional

Self-aggregation in aqueous solution of amphiphilic cationic calix[4] arenes. Potential use as vectors and nanocarriers

Ostos, FJ; Lebron, JA; Lopez-Cornejo, P; Lopez-Lopez, M; Garcia-Calderon, M; Garcia-Calderon, CB; Rosado, IV; Kalchenko, VI; Rodik, RV; Moya, ML

Vol: JOURNAL OF MOLECULAR LIQUIDS Revista Internacional
Revista Internacional

Structure-property relationships of D-mannitol-based cationic poly(amide triazoles) and their self-assembling complexes with DNA

Romero-Azogil, L; Benito, JM; Pinilla, IM; Hakkou, K; Martinez, MB; Canton, I; Lopez-Cornejo, P; Garcia-Calderon, CB; Rosado, IV; Garcia-Martin, MG; Benito, E

Vol: EUROPEAN POLYMER JOURNAL Revista Internacional
Revista Internacional

The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens

Rodriguez-Barbosa, JI; Schneider, P; Graca, L; Buhler, L; Perez-Simon, JA; del Rio, ML

Vol: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Revista Internacional
Revista Internacional

Treatment of Frail Older Adults and Elderly Patients With Philadelphia Chromosome-negative Acute Lymphoblastic Leukemia: Results of a Prospective Trial With Minimal Chemotherapy

Ribera, JM; Garcia, O; Chapchap, EC; Gil, C; Gonzalez-Campos, J; Barba, P; Amigo, ML; Moreno, MJ; Lavilla, E; Alonso, N; Bergua, JM; Tormo, M; Ribera, J; Sierra, M; Martinez-Carballeira, D; Mercadal, S; Hernandez-Rivas, JM; Vall-Llovera, F; Genesca, E; Cladera, A; Novo, A; Abella, E; Garcia-Cadenas, I; Monteserin, C; Bermudez, A; Piernas, S; Montesinos, P; Lopez, JL; Garcia-Guinon, A; Serrano, A; Martinez, MP; Olivares, M; Lopez, A; Serrano, J

Vol: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA Revista Internacional
Revista Internacional

Unique clinico-biological, genetic and prognostic features of adult early T-cell precursor acute lymphoblastic leukemia

Genesca, E; Morgades, M; Montesinos, P; Barba, P; Gil, C; Guardia, R; Moreno, MJ; Martinez-Carballeira, D; Garcia-Cadenas, I; Vives, S; Ribera, J; Gonzalez-Campos, J; Gonzalez-Gil, C; Zamora, L; Ramirez, JL; Diaz-Beya, M; Mercadal, S; Artola, MT; Cladera, A; Tormo, M; Bermudez, A; Vall-Llovera, F; Martinez, P; Amigo, ML; Monsalvo, S; Novo, A; Cervera, M; Garcia-Guinon, A; Junca, J; Ciudad, J; Orfao, A; Ribera, JM

Vol: HAEMATOLOGICA Revista Internacional
Revista Internacional

Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab

Garcia-Guerrero, E; Gotz, R; Doose, S; Sauer, M; Rodriguez-Gil, A; Nerreter, T; Kortum, KM; Perez-Simon, JA; Einsele, H; Hudecek, M; Danhof, S

Vol: LEUKEMIA Revista Internacional
2019
Revista Internacional

A precision medicine test predicts clinical response after idarubicin and cytarabine induction therapy in AML patients.

Martínez-Cuadrón D, Gil C, Serrano J, Rodríguez G, Pérez-Oteyza J, García-Boyero R, Jiménez-Bravo S, Vives S, Vidriales MB, Lavilla E, Pérez-Simón JA, Tormo M, Colorado M, Bergua J, López JA, Herrera P, Hernández-Campo P, Gorrochategui J, Primo D, Rojas JL, Villoria J, Moscardó F, Troconiz I, Linares Gómez M, Martínez-López J, Ballesteros J, Sanz M, Montesinos P, Spanish PETHEMA group

Vol: Leuk Res. Revista Internacional
Revista Internacional

Allocation to Matched Related or Unrelated Donor Results in Similar Clinical Outcomes without Increased Risk of Failure to Proceed to Transplant among Patients with Acute Myeloid Leukemia: A Retrospective Analysis from the Time of Transplant Approval.

Rodríguez-Arbolí E, Márquez-Malaver FJ, Rodríguez-Torres N, Caballero-Velázquez T, Escamilla-Gómez V, Calderón-Cabrera C, Falantes-González JF, Solé-Rodríguez M, García-Ramírez P, Moya-Arnao M, Carreras E, Espigado-Tocino I, Pérez-Simón JA

Vol: Biol Blood Marrow Transplant. Revista Internacional
Revista Internacional

An analysis of the impact of CD56 expression in de novo acute promyelocytic leukemia patients treated with upfront all-trans retinoic acid and anthracycline-based regimens.

Sobas M, Montesinos P, Boluda B, Bernal T, Vellenga E, Nomdedeu J, González-Campos J, Chillón M, Holowiecka A, Esteve J, Bergua J, González-Sanmiguel JD, Gil-Cortes C, Tormo M, Salamero O, Manso F, Fernández I, de la Serna J, Moreno MJ, Pérez-Encinas M, Krsnik I, Ribera JM, Escoda L, Lowenberg B, Sanz MA, PETHEMA, HOVON, PALG, and GATLA cooperative groups

Vol: Leuk Lymphoma. Revista Internacional
Revista Internacional

Cells Increases Their Clonogenic Capacity and Bone Marrow Lodging Ability.

Preciado S, Muntión S, Corchete LA, Ramos TL, de la Torre AG, Osugui L, Rico A, Espinosa-Lara N, Gastaca I, Díez-Campelo M, Del Cañizo C, Sánchez-Guijo F

Vol: Stem Cells. Revista Internacional
Revista Internacional

Chronic graft-versus-host disease could ameliorate the impact of adverse somatic mutations in patients with myelodysplastic syndromes and hematopoietic stem cell transplantation.

Caballero JC, Sánchez Barba M, Hernández Sánchez JM, Such E, Janusz K, Sanz G, Cabrero M, Chillón C, Cervera J, Hurtado AM, Jerez A, Calderón Cabrera C, Valcárcel D, Lumbreras E, Abáigar M, López Cadenas F, Hernández Rivas JM, Del Cañizo MC, Díez Campelo M

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Clinical significance of complex karyotype at diagnosis in pediatric and adult patients with de novo acute promyelocytic leukemia treated with ATRA and chemotherapy.

Labrador J, Luño E, Vellenga E, Brunet S, González-Campos J, Chillón MC, Holowiecka A, Esteve J, Bergua J, González-Sanmiguel JD, Gil C, Tormo M, Salamero O, Manso F, Fernández I, de laSerna J, Moreno MJ, Pérez-Encinas M, Krsnik I, Ribera JM, Cervera J, Calasanz MJ, Boluda B, Sobas M, Lowenberg B, Sanz MA, Montesinos P

Vol: Leuk Lymphoma Revista Internacional
Revista Internacional

Dual cholinergic signals regulate daily migration of hematopoietic stem cells and leukocytes.

García-García A, Korn C, García-Fernández M, Domingues O, Villadiego J, Martín-Pérez D, Isern J, Bejarano-García JA, Zimmer J, Pérez-Simón JA, Toledo-Aral JJ, Michel T, Airaksinen MS, Méndez-Ferrer S

Vol: Blood. Revista Internacional
Revista Internacional

Eosinophils with ring-shaped nuclei in a patient treated with adalimumab

Morales-Camacho RM, Prats-Martín C

Vol: Blood. Revista Internacional
Revista Internacional

F-FDG PET/CT for extramedullary relapse of acute leukemia of ambiguous lineage.

de Bonilla Damiá Á, Fernández López R, Acevedo Báñez I, Calderón Cabrera C, Molinos Quintana A, Borrego Dorado I

Vol: Rev Esp Med Nucl Imagen Mol. Revista Internacional
Revista Internacional

Frequency, characteristics, and outcome of PTLD after allo-SCT: A multicenter study from the Spanish group of blood and marrow transplantation (GETH).

García-Cadenas I, Yáñez L, Jarque I, Martino R, Pérez-Simón JA, Valcárcel D, Sanz J, Bermúdez A, Muñoz C, Calderón-Cabrera C, García E, Alonso L, Suárez-Lledó M, González Vicent M, Heras I, Viguria MC, Batlle M, Vázquez L, López J, Solano C, Spanish group of blood and marrow transplantation (GETH)

Vol: Eur J Haematol. Revista Internacional
Revista Internacional

HVEM, a cosignaling molecular switch, and its interactions with BTLA, CD160 and LIGHT.

Rodriguez-Barbosa JI, Schneider P, Weigert A, Lee KM, Kim TJ, Perez-Simon JA, Del Rio ML

Vol: Cell Mol Immunol. Revista Internacional
Revista Internacional

Haploidentical transplantation and posttransplant cyclophosphamide for treating aplastic anemia patients: a report from the EBMT Severe Aplastic Anemia Working Party.

Prata PH, Eikema DJ, Afansyev B, Bosman P, Smiers F, Diez-Martin JL, Arrais-Rodrigues C, Koc Y, Poiré X, Sirvent A, Kröger N, Porta F, Holter W, Bloor A, Jubert C, Ganser A, Tanase A, Ménard AL, Pioltelli P, Pérez-Simón JA, Ho A, Aljurf M, Russell N, Labussiere-Wallet H, Kerre T, Rocha V, Socié G, Risitano A, Dufour C, Peffault de Latour R, SAA WP of the EBMT

Vol: Bone Marrow Transplant. Revista Internacional
Revista Internacional

Human acute myeloid leukemia cells express Neurokinin-1 receptor, which is involved in the antileukemic effect of Neurokinin-1 receptor antagonists.

Molinos-Quintana A, Trujillo-Hacha P, Piruat JI, Bejarano-García JA, García-Guerrero E, Pérez-Simón JA, Muñoz M

Vol: Invest New Drugs. Revista Internacional
Revista Internacional

Immediate Effects of Dasatinib on the Migration and Redistribution of Naïve and Memory Lymphocytes Associated With Lymphocytosis in Chronic Myeloid Leukemia Patients

Colom-Fernández B, Kreutzman A, Marcos-Jiménez A, García-Gutiérrez V, Cuesta-Mateos C, Portero-Sainz I, Pérez-García Y, Casado LF, Sánchez-Guijo F, Martínez-López J, Ayala RM, Boqué C, Xicoy B, Montero I, Soto C, Paz R, Silva G, Vega-Piris L, Steegmann JL, Muñoz-Calleja C

Vol: Front Pharmacol. Revista Internacional
Revista Internacional

Incidence and outcome after first molecular versus overt recurrence in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia included in the ALL Ph08 trial from the Spanish PETHEMA Group.

Ribera JM, García O, Moreno MJ, Barba P, García-Cadenas I, Mercadal S, Montesinos P, Barrios M, González-Campos J, Martínez-Carballeira D, Gil C, Ribera J, Vives S, Novo A, Cervera M, Serrano J, Lavilla E, Abella E, Tormo M, Amigo ML, Artola MT, Genescà E, Bravo P, García-Belmonte D, García-Guiñón A, Hernández-Rivas JM, Feliu E, PETHEMA Group of the Spanish Society of Hematology

Vol: Cancer. Revista Internacional
Revista Internacional

Increased survival due to lower toxicity for high-risk T-cell acute lymphoblastic leukemia patients in two consecutive pediatric-inspired PETHEMA trials.

Barba P, Morgades M, Montesinos P, Gil C, Fox ML, Ciudad J, Moreno MJ, González-Campos J, Genescà E, Martínez-Carballeira D, Martino R, Vives S, Guardia R, Mercadal S, Artola MT, Cladera A, Tormo M, Esteve J, Bergua J, Vall-Llovera F, Ribera J, Martínez-Sanchez P, Amigo ML, Bermúdez A, Calbacho M, Hernández-Rivas JM, Feliu E, Orfao A, Ribera JM

Vol: Eur J Haematol. Revista Internacional
Revista Internacional

Joint status in Spanish haemophilia B patients assessed using the Haemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) score.

Jiménez-Yuste V, Álvarez-Román MT, Martín-Salces M, De la Corte-Rodríguez H, Altisent C, Parra R, Núñez R, Pérez R, García-Candel F, Bonanad S, Querol F, Alonso N, Fernández-Mosteirín N, López-Ansoar E, García-Frade LJ, Bermejo N, Pérez-González N, Gutiérrez-Pimentel MJ, Martinoli C, Fernández-Arias I, Kim HK

Vol: Haemophilia. Revista Internacional
Revista Internacional

Molecular profiling refines minimal residual disease-based prognostic assessment in adults with Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia

Ribera J, Zamora L, Morgades M, Vives S, Granada I, Montesinos P, Gomez-Segui I, Mercadal S, Guardia R, Nomdedeu J, Pratcorona M, Tormo M, Martinez-Lopez J, Hernandez-Rivas JM, Ciudad J, Orfao A, Gonzalez-Campos J, Barba P, Escoda L, Esteve J, Genesca E, Sole F, Feliu E, Ribera JM

Vol: Genes Chromosomes Cancer. Revista Internacional
Revista Internacional

Neutrophil faggot cells and inv(16): not such a fortuitous association?

Garrastazul-Sánchez MP, Vilches-Moreno M, Fernández-Valle MC, Marchante-Cepillo I, Prats-Martín C, Bernal R, Morales-Camacho RM

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Neutrophil faggot cells and inv(16): not such a fortuitous association? (1)

Garrastazul-Sánchez MP, Vilches-Moreno M, Fernández-Valle C, Marchante-Cepillo I, Prats-Martín C, Bernal R, Morales-Camacho R

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Nuclear protrusion in dysplastic micromegakaryocytes.

Pérez-Ortega L, Morales-Camacho RM

Vol: Blood. Revista Internacional
Revista Internacional

Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae.

Ramos-Sáenz A, González-Álvarez D, Rodríguez-Galán O, Rodríguez-Gil A, Gaspar SG, Villalobo E, Dosil M, de la Cruz J

Vol: RNA. Revista Internacional
Revista Internacional

Predicting long-term disease control in transplant-ineligible patients with multiple myeloma: impact of an MGUS-like signature

Rodríguez-Otero P, Mateos MV, Martínez-López J, Hernández MT, M. Ocio E, Rosiñol L, Martínez R, Teruel AI, Gutiérrez NC,Bargay J, Bengoechea E, González Y, Pérez de Oteyza J, Gironella M, Nuñez-Córdoba JM, Encinas C, Martín J, Cabrera C, Palomera L, de Arriba F, Cedena MT, Puig N, Oriol A, Paiva B, Bladé J, Lahuerta JJ, San Miguel JF

Vol: Blood Cancer J. Revista Internacional
Revista Internacional

Preparation and characterization of metallomicelles of Ru(II). Cytotoxic activity and use as vector.

Lebrón JA, Ostos FJ, López-López M, Moyá ML, Kardell O, Sánchez A, Carrasco CJ, García-Calderón M, García-Calderón CB, Rosado IV, López-Cornejo P

Vol: Colloids Surf B Biointerfaces. Revista Internacional
Revista Internacional

Real life outcomes of patients aged ≥75 years old with acute promyelocytic leukemia: experience of the PETHEMA registry.

Salamero O, Martínez-Cuadrón D, Sobas M, Benavente C, Vives S, De la Serna J, Pérez-Encinas M, Escoda L, Gil C, Brunet S, Ramos F, Esteve J, Amigo M, Krsnik I, Manso F, Arias J, González-Campos J, Serrano J, Oleksiuk J, Barrios M, García-Boyero R, Novo A, Sanz MA, Montesinos P, PETHEMA and PALG Groups

Vol: Leuk Lymphoma. Revista Internacional
Revista Internacional

Relationship of thromboelastography and conventional clotting test values with severe bleeding in critically ill patients with coagulopathy: A prospective study.

Casado-Méndez M, Fernandez-Pacheco J, Arellano-Orden V, Rodríguez-Martorell FJ, Díaz-Martín A, Pastor de Las Heras Á, Dusseck-Brutus R, Pérez-Torres I, Leal-Noval SR

Vol: Int J Lab Hematol. Revista Internacional
Revista Internacional

Response to Novel Drugs before and after Allogeneic Stem Cell Transplantation in Patients with Relapsed Multiple Myeloma.

López-Corral L, Caballero-Velázquez T, López-Godino O, Rosiñol L, Pérez-Vicente S, Fernandez-Avilés F, Krsnik I, Morillo D, Heras I, Morgades M, Rifon JJ, Sampol A, Iniesta F, Ocio EM, Martin J, Rovira M, Cabero M, Castilla-Llorente C, Ribera JM, Torres-Juan M, Moraleda JM, Martinez C, Vázquez A, Gutierrez G, Caballero D, San Miguel JF, Mateos MV, Pérez-Simón JA

Vol: Biol Blood Marrow Transplant. Revista Internacional
Revista Internacional

Role of urine immunofixation in the complete response assessment of MM patients other than light-chain-only disease.

Lahuerta JJ, Jiménez-Ubieto A, Paiva B, Martínez-López J, González-Medina J, López-Anglada L, Cedena MT, Puig N, Oriol A, Blanchard MJ, Ríos R, Martin J, Martínez R, Sureda A, Hernández MT, de la Rubia J, Krsnik I, Cabañas V, Palomera L, Bargay J, Mateos MV, Rosiñol L, San Miguel JF, Blade J

Vol: Blood. Revista Internacional
Revista Internacional

Single-agent daratumumab in patients with relapsed and refractory multiple myeloma requiring dialysis: results of a Spanish retrospective, multicentre study.

Cejalvo MJ, Legarda M, Abella E, Cabezudo E, Encinas C, García-Feria A, Gironella M, Iñigo B, Martín J, Ribas P, Ruíz MÁ, González Y, Vicuña I, Ramírez Á, Fernández P, de la Rubia J

Vol: Br J Haematol. Revista Internacional
Revista Internacional

The poor prognosis of low hypodiploidy in adults with B-cell precursor acute lymphoblastic leukaemia is restricted to older adults and elderly patients.

Ribera J, Granada I, Morgades M, Vives S, Genescà E, González C, Nomdedeu J, Escoda L, Montesinos P, Mercadal S, Coll R, González-Campos J, Abella E, Barba P, Bermúdez A, Gil C, Tormo M, Pedreño M, Martínez-Carballeira D, Hernández-Rivas JM, Orfao A, Martínez-López J, Esteve J, Bravo P, Garcia-Guiñon A, Debén G, Moraleda JM, Queizán JA, Ortín X, Moreno MJ, Feliu E, Solé F, Ribera JM, PETHEMA Group, Spanish Society of Haematology

Vol: Br J Haematol. Revista Internacional
Revista Internacional

Update on Molecular Testing in von Willebrand Disease.

Batlle J, Pérez-Rodríguez A, Corrales I, Borràs N, Costa Pinto J, López-Fernández MF, Vidal F, PCM-EVW-ES Investigators Team

Vol: Semin Thromb Hemost. Revista Internacional
Revista Internacional

Vitamin D Modifies the Incidence of Graft-versus-Host Disease after Allogeneic Stem Cell Transplantation Depending on the Vitamin D Receptor (VDR) Polymorphisms.

Carrillo-Cruz E, García-Lozano JR, Márquez-Malaver FJ, Sánchez-Guijo FM, Montero Cuadrado I, Ferra I Coll C, Valcárcel D, López-Godino O, Cuesta M, Parody R, López-Corral L, Alcoceba M, Caballero-Velázquez T, Rodríguez-Gil A, Bejarano-García JA, Ramos TL, Pérez-Simón JA

Vol: Clin Cancer Res. Revista Internacional
2018
Revista Internacional

A phase I-II study of plerixafor in combination with fludarabine, idarubicin, cytarabine, and G-CSF (PLERIFLAG regimen) for the treatment of patients with the first early-relapsed or refractory acute myeloid leukemia.

Martínez-Cuadrón D, Boluda B, Martínez P, Bergua J, Rodríguez-Veiga R, Esteve J, Vives S, Serrano J, Vidriales B, Salamero O, Cordón L, Sempere A, Jiménez-Ubieto A, Prieto-Delgado J, Díaz-Beyá M, Garrido A, Benavente C, Pérez-Simón JA, Moscardó F, Sanz MA, Montesinos P, CETLAM and PETHEMA groups.

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Administration of taurolidine-citrate lock solution for prevention of central venous catheter infection in adult neutropenic haematological patients: a randomised, double-blinded, placebo-controlled trial (TAURCAT).

Gudiol C, Nicolae S, Royo-Cebrecos C, Aguilar-Guisado M, Montero I, Martín-Gandul C, Perayre M, Berbel D, Encuentra M, Arnan M, Cisneros-Herreros JM, Carratalà J.

Vol: Trials. Revista Internacional
Revista Internacional

Basophil-lineage commitment in acute promyelocytic leukemia predicts for severe bleeding after starting therapy.

Matarraz S, Leoz P, Fernández C, Colado E, Chillón MC, Vidriales MB, González M, Rivera D, Osuna CS, Caballero-Velázquez T, Van Der Velden V, Jongen-Lavrencic M, Gutiérrez O, Bermejo AY, Alonso LG, García MB, De Ramón Sánchez C, García-Donas G, Mateo AG, Recio I, Sánchez-Real J, Mayado A, Gutiérrez ML, Bárcena P, Barrena S, López A, Van Dongen J, Orfao A.

Vol: Mod Pathol. Revista Internacional
Revista Internacional

Bone marrow erythrocyte and neutrophil phagocytosis and cannibalism by neuroendocrine carcinoma

González-Molina W, Ávila-Polo R, Morales-Camacho RM, Vargas MT, Bernal R, Prats-Martín C.

Vol: Br J Haematol. Revista Internacional
Revista Internacional

Clinical association of anti-glutathione S-transferase T1 antibodies and de novo immune hepatitis after hematopoietic cell transplantation.

Aguado-Domínguez E, Sousa JM, Pérez-Simón JA, Aguilera I.

Vol: Dig Liver Dis. Revista Internacional
Revista Internacional

Comparison of intensive, pediatric-inspired therapy with non-intensive therapy in older adults aged 55-65 years with Philadelphia chromosome-negative acute lymphoblastic leukemia.

Ribera JM, García O, Gil C, Mercadal S, García-Cadenas I, Montesinos P, Barba P, Vives S, González-Campos J, Tormo M, Esteve J, López A, Moreno MJ, Ribera J, Alonso N, Bermúdez A, Amigo ML, Genescà E, García D, Vall-Llovera F, Bergua JM, Guàrdia R, Monteserín MC, Bernal T, Calbacho M, Martínez MP, Feliu E, PETHEMA Group.

Vol: Leuk Res Revista Internacional
Revista Internacional

De novo recipient-specific Glutathione S-transferase T1 antibody development after HLA-identical hematopoietic cell transplantation.

Martínez-Bravo MJ, Sánchez B, Acevedo MJ, Pérez-Simón JA, Núñez-Roldán A, Aguilera I.

Vol: Transpl Immunol. Revista Internacional
Revista Internacional

Differential prognostic impact of GELTAMO-IPI in cell of origin subtypes of Diffuse Large B Cell Lymphoma as defined by the Hans algorithm

Montalbán C, Díaz-López A, Martín A, Baile M, Sánchez JM, Sancho JM, García O, Novelli S, Monter-Rovira A, Salar A, Bastos M, Gutiérrez A, Bento L, Córdoba R, Arquero T, González de Villambrosia S, Barranco G, De Oña R, López Guillermo A, Rodríguez Salazar MJ, Domínguez JF, Fernández R, Queizan JA, Rodríguez J, Abraira V, García JF, GELTAMO-IPI Project Investigators.

Vol: Br J Haematol. Revista Internacional
Revista Internacional

Early myeloma-related death in elderly patients: development of a clinical prognostic score and evaluation of response sustainability role.

Rodríguez-Otero P, Mateos MV, Martínez-López J, Martín-Calvo N, Hernández MT, Ocio EM, Rosiñol L, Martínez R, Teruel AI, Gutiérrez NC, Bargay J, Bengoechea E, González Y, de Oteyza JP, Gironella M, Encinas C, Martín J, Cabrera C, Palomera L, de Arriba F, Cedena MT, Paiva B, Puig N, Oriol A, Bladé J, Lahuerta JJ, San Miguel JF.

Vol: Leukemia. Revista Internacional
Revista Internacional

Efficacy and safety of native versus pegylated Escherichia coli asparaginase for treatment of adults with high-risk, Philadelphia chromosome-negative acute lymphoblastic leukemia.

Ribera JM, Morgades M, Montesinos P, Martino R, Barba P, Soria B, Bermúdez A, Moreno MJ, González-Campos J, Vives S, Gil C, Abella E, Guàrdia R, Martínez-Carballeira D, Martínez-Sánchez P, Amigo ML, Mercadal S, Serrano A, López-Martínez A, Vall-Llovera F, Sánchez-Sánchez MJ, Peñarrubia MJ, Calbacho M, Méndez JA, Bergua J, Cladera A, Tormo M, García-Belmonte D, Feliu E, Ciudad J, Orfao A, PETHEMA Group, Spanish Society of Hematology.

Vol: Leuk Lymphoma. Revista Internacional
Revista Internacional

Eosinophil phagocytosis in advanced systemic mastocytosis with eosinophilia.

Morales-Camacho RM, Villanueva-Herraiz S, Prats-Martín C, Borrero JJ, Bernal R, Vargas MT.

Vol: Br J Haematol. Revista Internacional
Revista Internacional

Evaluation of Parameters Related to the Probability of Leukemic Progression in Patients With Lower-Risk Myelodysplastic Syndrome.

Falantes JF, Márquez-Malaver FJ, Calderón-Cabrera C, Pedrote B, Martino ML, González J, Espigado I, Pérez-Simón JA.

Vol: Clin Lymphoma Myeloma Leuk Revista Internacional
Revista Internacional

Formaldehyde-assisted Isolation of Regulatory Elements to Measure Chromatin Accessibility in Mammalian Cells.

Rodríguez-Gil A, Riedlinger T, Ritter O, Saul VV, Schmitz ML.

Vol: J Vis Exp Revista Internacional
Revista Internacional

Frequency and clinical impact of CDKN2A/ARF/CDKN2B gene deletions as assessed by in-depth genetic analyses in adult T cell acute lymphoblastic leukemia.

. Genescà E, Lazarenkov A, Morgades M, Berbis G, Ruíz-Xivillé N, Gómez-Marzo P, Ribera J, Juncà J, González-Pérez A, Mercadal S, Guardia R, Artola MT, Moreno MJ, Martínez-López J, Zamora L, Barba P, Gil C, Tormo M, Cladera A, Novo A, Pratcorona M, Nomdedeu J, González-Campos J, Almeida M, Cervera J, Montesinos P, Batlle M, Vives S, Esteve J, Feliu E, Solé F, Orfao A, Ribera JM.

Vol: J Hematol Oncol. Revista Internacional
Revista Internacional

Frequency and prognostic significance of additional cytogenetic abnormalities to the Philadelphia chromosome in young and older adults with acute lymphoblastic leukemia.

Motlló C, Ribera JM, Morgades M, Granada I, Montesinos P, Mercadal S, González-Campos J, Moreno MJ, Barba P, Cervera M, Barrios M, Novo A, Bernal T, Hernández-Rivas JM, Abella E, Amigo ML, Tormo M, Martino R, Lavilla E, Bergua J, Serrano A, García-Belmonte D, Guàrdia R, Grau J, Feliu E, PETHEMA Group, Spanish Society of Hematology.

Vol: Leuk Lymphoma Revista Internacional
Revista Internacional

Genotoxicity of tetrahydrofolic acid to hematopoietic stem and progenitor cells.

García-Calderón CB, Bejarano-García JA, Tinoco-Gago I, Castro MJ, Moreno-Gordillo P, Piruat JI, Caballero-Velázquez T, Pérez-Simón JA, Rosado IV.

Vol: Cell Death Differ. Revista Internacional
Revista Internacional

IMiDs mobilize acute myeloid leukemia blasts to peripheral blood through downregulation of CXCR4 but fail to potentiate AraC/Idarubicin activity in preclinical models of non del5q/5q- AML.

López-Millán B, Díaz de la Guardia R, Roca-Ho H, Anguita E, Islam ABMMK, Romero-Moya D, Prieto C, Gutiérrez-Agüera F, Bejarano-García JA, Pérez-Simón JA, Costales P, Rovira M, Marín P, Menéndez S, Iglesias M, Fuster JL, Urbano-Ispizua A, Anjos-Afonso F, Bueno C, Menéndez P.

Vol: Oncoimmunology Revista Internacional
Revista Internacional

Internuclear bridging outside of primary myelodysplasia and congenital dyserythropoietic anemia.

Rojas-Martínez JA, Morales-Camacho RM.

Vol: Blood. Revista Internacional
Revista Internacional

KIT D816V- chronic myelomonocytic leukemia progressing to KIT D816V+ associated to mast cell leukemia responding to allogeneic hematopoietic cell transplantation.

Prats-Martín C, Jiménez-Guerrero P, Morales-Camacho RM, Caballero-Velázquez T, Vargas MT, Pérez O, Montero I, Falantes J, Burillo-Sanz S, Carrillo E, Borrero JJ, Bernal R, Pérez-Simón JA.

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Long-term outcome of older patients with newly diagnosed de novo acute promyelocytic leukemia treated with ATRA plus anthracycline-based therapy.

Martínez-Cuadrón D, Montesinos P, Vellenga E, Bernal T, Salamero O, Holowiecka A, Brunet S, Gil C, Benavente C, Ribera JM, Pérez-Encinas M, De la Serna J, Esteve J, Rubio V, González-Campos J, Escoda L, Amutio ME, Arnan M, Arias J, Negri S, Lowënberg B, Sanz MA.

Vol: Leukemia. Revista Internacional
Revista Internacional

MLL-rearranged acute myeloid leukemia: Influence of the genetic partner in allo-HSCT response and prognostic factor of MLL 3' region mRNA expression.

Burillo-Sanz S, Morales-Camacho RM, Caballero-Velázquez T, Carrillo E, Sánchez J, Pérez-López O, Pérez de Soto I, González Campos J, Prats-Martín C, Bernal R, Vargas MT.

Vol: Eur J Haematol. Revista Internacional
Revista Internacional

Mesenchymal Stromal Cell Irradiation Interferes with the Adipogenic/Osteogenic Differentiation Balance and Improves Their Hematopoietic-Supporting Ability.

Preciado S, Muntión S, Rico A, Pérez-Romasanta LA, Ramos TL, Ortega R, Borrajo J, Corchete LA, Rodríguez C, Díez-Campelo M, Sánchez-Abarca LI, Del Cañizo MC, Sánchez-Guijo F.

Vol: Biol Blood Marrow Transplant. Revista Internacional
Revista Internacional

Noninvasive prenatal diagnosis by cell-free DNA screening for fetomaternal HPA-1a platelet incompatibility.

Ferro M, Mácher HC, Fornés G, Martín-Sánchez J, Jiménez-Arriscado P, Molinero P, Pérez-Simón JA, Guerrero JM, Rubio A.

Vol: Transfusion. Revista Internacional
Revista Internacional

PD-1 genotype of the donor is associated with acute graft-versus-host disease after HLA-identical sibling donor stem cell transplantation.

Santos N, Rodríguez-Romanos R, de la Cámara R, Brunet S, Nieto JB, Buño I, Martínez C, Jiménez-Velasco A, Vallejo C, González M, Solano C, Ferrá C, Sampol A, Pérez-Simón JA, López-Jiménez J, Díez JL, Gallardo D, GvHD/Immunotherapy Working Party of the Spanish Group of Hematopoietic Transplant (GETH).

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Prospective randomized trial of 5 days azacitidine versus supportive care in patients with lower-risk myelodysplastic syndromes without 5q deletion and transfusion-dependent anemia.

Sánchez-García J, Falantes J, Medina Pérez A, Hernández-Mohedo F, Hermosín L, Torres-Sabariego A, Bailén A, Hernández-Sánchez JM, Solé Rodríguez M, Casaño FJ, Calderón C, Labrador M, Vahí M, Serrano J, Lumbreras E, Hernández-Rivas JM, Grupo Andaluz SMD.

Vol: Leuk Lymphoma. Revista Internacional
Revista Internacional

RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation.

Buchrieser J, Oliva-Martín MJ, Moore MD, Long JCD, Cowley SA, Pérez-Simón JA, James W, Venero JL.

Vol: Cell Death Dis. Revista Internacional
Revista Internacional

Reduced intensity conditioning increases risk of severe cGVHD: identification of risk factors for cGVHD in a multicenter setting.

Afram G, Simón JAP, Remberger M, Caballero-Velázquez T, Martino R, Piñana JL, Ringden O, Esquirol A, López-Corral L, García I, López-Godino O, Sierra J, Caballero D, Ljungman P, Vázquez L, Hägglund H.

Vol: Med Oncol Revista Internacional
Revista Internacional

Reduced-intensity conditioning haematopoietic stem cell transplantation in genetic diseases: Experience of the Spanish Working Group for Bone Marrow Transplantation in Children.

López-Granados L, Torrent M, Sastre A, González-Vicent M, Díaz de Heredia C, Argilés B, Pascual A, Pérez-Hurtado JM, Sisinni L, Díaz MÁ, Elorza I, Dasí MA, Badell I.

Vol: An Pediatr (Barc). Revista Internacional
Revista Internacional

Reliability of the portable coagulometer qLabs to accurately measure the activated thromboplastin time and international normalized ratio: a prospective study in critically ill patients.

Casado-Méndez M, Arellano-Orden V, Muñoz-Gómez M, Rodríguez-Martorell FJ, Cayuela A, Pastor de Las Heras Á, Díaz Martín A, Pérez Torres I, Leal-Noval SR.

Vol: Blood Coagul Fibrinolysis. Revista Internacional
Revista Internacional

Selection of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients Through the Identification of T-Cells Capable to Establish Stable Interactions With the Leukemic Cells: "Doublet Technology".

García-Guerrero E, Sánchez-Abarca LI, Domingo E, Ramos TL, Bejarano-García JA, González-Campos JA, Caballero-Velázquez T, Pérez-Simón JA.

Vol: Front Immunol Revista Internacional
Revista Internacional

Severe granulocytic dysplasia with vacuolar rosettes in a myelodysplastic syndrome with low-copy KMT2A gain

. Rodríguez-Arbolí E, Morales-Camacho RM, Prats-Martín C, Vargas MT, Montero MI, Bernal R.

Vol: Br J Haematol. Revista Internacional
Revista Internacional

Therapeutic implications of NK cell regulation of allogeneic CD8 T cell-mediated immune responses stimulated through the direct pathway of antigen presentation in transplantation.

Rodríguez-Barbosa JI, Ferreras MC, Buhler L, Jones ND, Schneider P, Pérez-Simón JA, Del Río ML.

Vol: MAbs Revista Internacional
Revista Internacional

Vitamin D: Effect on Haematopoiesis and Immune System and Clinical Applications.

Medrano M, Carrillo-Cruz E, Montero I, Pérez-Simón JA.

Vol: Int J Mol Sci. Revista Internacional
2017
Revista Internacional

Acquired haemophilia: Epidemiology, clinical presentation, diagnosis and treatment

Mingot-Castellano ME, Núñez R, Rodríguez-Martorell FJ.

Vol: Med Clin (Barc) Revista Internacional
Revista Internacional

Assessment of dry eye in a GVHD murine model: Approximation through tear osmolarity measurement

Martínez-Carrasco R, Sánchez-Abarca LI, Nieto-Gómez C, García EM, Ramos TL, Velasco A, Sánchez-Guijo F, Aijón J, Hernández-Galilea E

Vol: Exp Eye Res. Revista Internacional
Revista Internacional

Azacitidine improves clinical outcomes in older patients with acute myeloid leukaemia with myelodysplasia-related changes compared with conventional care regimens.

Seymour JF, Döhner H, Butrym A, Wierzbowska A, Selleslag D, Jang JH, Kumar R, Cavenagh J, Schuh AC, Candoni A, Récher C, Sandhu I, Del Castillo TB, Al-Ali HK, Falantes J, Stone RM, Minden MD, Weaver J, Songer S, Beach CL, Dombret H.

Vol: BMC Cancer Revista Internacional
Revista Internacional

Candida parapsilosis misleading the automated absolute and differential white blood cell count

Verdesoto-Cozzarelli S, Prats-Martín C, Morales-Camacho RM, Pérez de Soto C, Ruiz M, de Blas JM, Bernal R, Pérez-Simón JA.

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Cannabinoid derivatives exert a potent anti-myeloma activity both in vitro and in vivo.

Barbado MV, Medrano M, Caballero-Velázquez T, Álvarez-Laderas I, Sánchez-Abarca LI, García-Guerrero E, Martín-Sánchez J, Rosado IV, Piruat JI, González-Naranjo P, Campillo NE, Páez JA, Pérez-Simón JA.

Vol: Int J Cancer. Revista Internacional
Revista Internacional

Circulating hypergranular neoplastic cells: not always leukemic promyelocytes

Prats-Martín C, Morales-Camacho RM.

Vol: Blood. Revista Internacional
Revista Internacional

Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study.

. Almeida AM, Prebet T, Itzykson R, Ramos F, Al-Ali H, Shammo J, Pinto R, Maurillo L, Wetzel J, Musto P, Van De Loosdrecht AA, Costa MJ, Esteves S, Burgstaller S, Stauder R, Autzinger EM, Lang A, Krippl P, Geissler D, Falantes JF, Pedro C, Bargay J, Deben G, Garrido A, Bonanad S, Díez-Campelo M, Thepot S, Ades L, Sperr WR, Valent P, Fenaux P, Sekeres MA, Greil R, Pleyer L.

Vol: Int J Mol Sci. Revista Internacional
Revista Internacional

Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia: the importance of characterizing ABL1 mutations in cerebrospinal fluid.

Sánchez R, Ayala R, Alonso RA, Martínez MP, Ribera J, García O, Sánchez-Pina J, Mercadal S, Montesinos P, Martino R, Barba P, González-Campos J, Barrios M, Lavilla E, Gil C, Bernal T, Escoda L, Abella E, Amigo ML, Moreno MJ, Bravo P, Guàrdia R, Hernández-Rivas JM, García-Guiñón A, Piernas S, Ribera JM, Martínez-López J.

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis.

Sarmiento Maldonado M, Ramírez Villanueva P, Bertín Cortes-Monroy P, Jara Arias V, Soto Donoso K, Uribe González P, Ocqueteau Tachini M, Pérez-Simón JA.

Vol: Exp Hematol Oncol. Revista Internacional
Revista Internacional

Diagnostic screening of paroxysmal nocturnal hemoglobinuria: Prospective multicentric evaluation of the current medical indications

. Morado M, Freire Sandes A, Colado E, Subirá D, Isusi P, Soledad Noya M, Belén Vidriales M, Sempere A, Ángel Díaz J, Minguela A, Álvarez B, Serrano C, Caballero T, Rey M, Pérez Corral A, Cristina Fernández Jiménez M, Magro E, Lemes A, Benavente C, Bañas H, Merino J, Castejón C, Gutiérrez O, Rabasa P, Vescosi Gonçalves M, Pérez-Andrés M, Orfao A, PNH working group of the Iberian Society of Cytometry (SIC).

Vol: Cytometry B Clin Cytom. Revista Internacional
Revista Internacional

Donor CTLA-4 Genotype Modulates the Immune Response to Minor Histocompatibility Antigen Mismatches

Gallardo D, Bosch-Vizcaya A, Rodríguez-Romanos R, Santos N, Buño I, de la Cámara R, Brunet S, Jiménez-Velasco A, González M, Nieto JB, Martínez-Laperche C, Vallejo C, Ferrá C, Sampol A, López-Jiménez J, Pérez-Simón JA, Martínez C, Díez JL, GvHD/Immunotherapy Committee of the Spanish Hematopoietic Transplant Group.

Vol: Biol Blood Marrow Transplant. Revista Internacional
Revista Internacional

Excess mortality in the myelodysplastic syndromes

Nomdedeu M, Pereira A, Ramos F, Valcárcel D, Costa D, Arnan M, Calvo X, Pomares H, Luño E, Díaz-Campelo M, Collado R, de Paz R, Falantes JF, Pedro C, Marco J, Oirtzabal I, Sánchez-García J, Tormo M, Cedena MT, Nomdedeu B, Sanz G, Spanish MDS Group.

Vol: Am J Hematol. Revista Internacional
Revista Internacional

HDAC8 overexpression in mesenchymal stromal cells from JAK2+ myeloproliferative neoplasms: a new therapeutic target?

Ramos TL, Sánchez-Abarca LI, Redondo A, Hernández-Hernández Á, Almeida AM, Puig N, Rodríguez C, Ortega R, Preciado S, Rico A, Muntión S, Porras JRG, Del Cañizo C, Sánchez-Guijo F.

Vol: Oncotarget. Revista Internacional
Revista Internacional

Intravascular lymphoma: look through the small vessels

Prats-Martín C, Franco-Macías E, Morales-Camacho RM, Pérez O, Vargas MT, de la Cruz Vicente F, Borrero JJ, Bernal R, Pérez-Simón JA.

Vol: Ann Hematol. Revista Internacional
Revista Internacional

Kon-tiki enhances PS2 integrin adhesion and localizes its ligand, Thrombospondin, in the myotendinous junction.

Pérez-Moreno JJ, Espina-Zambrano AG, García-Calderón CB, Estrada B.

Vol: J Cell Sci. Revista Internacional
Revista Internacional

Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study.

Barzaghi F, Amaya Hernández LC, Neven B, Ricci S, Kucuk ZY, Bleesing JJ, Nademi Z, Slatter MA, Ulloa ER, Shcherbina A, Roppelt A, Worth A, Silva J, Aiuti A, Murguia-Favela L, Speckmann C, Carneiro-Sampaio M, Fernandes JF, Baris S, Ozen A, Karakoc-Aydiner E, Kiykim A, Schulz A, Steinmann S, Notarangelo LD, Gambineri E, Lionetti P, Shearer WT, Forbes LR, Martínez C, Moshous D, Blanche S, Fisher A, Ruemmele FM, Tissandier C, Ouachee-Chardin M, Rieux-Laucat F, Cavazzana M, Qasim W, Lucarelli B, Albert MH, Kobayashi I, Alonso L, Díaz De Heredia C, Kanegane H, Lawitschka A, Seo JJ, González-Vicent M, Díaz MA, Goyal RK, Sauer MG, Yesilipek A, Kim M, Yilmaz-Demirdag Y, Bhatia M, Khlevner J, Richmond Padilla EJ, Martino S, Montin D, Neth O, Molinos-Quintana A, Valverde-Fernández J, Broides A, Pinsk V, Ballauf A, Haerynck F, Bordon V, Dhooge C, García-Lloret ML, Bredius RG, Kałwak K, Haddad E, Seidel MG, Duckers G, Pai SY, Dvorak CC, Ehl S, Locatelli F, Goldman F, Gennery AR, Cowan MJ, Roncarolo MG, Bacchetta R, Primary Immune Deficiency Treatment Consortium (PIDTC) and the Inborn Errors Working Party (IEWP) of the European Society for Blood and Marrow Transplantation (EBMT).

Vol: J Allergy Clin Immunol. Revista Internacional
Revista Internacional

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang CJ, Vázquez A, Patel KJ.

Vol: Nature. Revista Internacional
Revista Internacional

Mesenchymal stromal cells (MSC) from JAK2+ myeloproliferative neoplasms differ from normal MSC and contribute to the maintenance of neoplastic hematopoiesis.

Ramos TL, Sánchez-Abarca LI, Rosón-Burgo B, Redondo A, Rico A, Preciado S, Ortega R, Rodríguez C, Muntión S, Hernández-Hernández Á, De Las Rivas J, González M, González Porras JR, Del Cañizo C, Sánchez-Guijo F.

Vol: PLoS One. Revista Internacional
Revista Internacional

Modulation of cytotoxic responses by targeting CD160 prolongs skin graft survival across major histocompatibility class I barrier.

Del Río ML, Bravo Moral AM, Fernández-Renedo C, Buhler L, Pérez-Simón JA, Chaloin O, Álvarez Nogal R, Fernández-Caso M, Rodríguez-Barbosa JI.

Vol: Transl Res Revista Internacional
Revista Internacional

Optimisation of empirical antimicrobial therapy in patients with haematological malignancies and febrile neutropenia (How Long study): an open-label, randomised, controlled phase 4 trial.

Aguilar-Guisado M, Espigado I, Martín-Peña A, Gudiol C, Royo-Cebrecos C, Falantes J, Vázquez-López L, Montero MI, Rosso-Fernández C, de la Luz Martino M, Parody R, González-Campos J, Garzón-López S, Calderón-Cabrera C, Barba P, Rodríguez N, Rovira M, Montero-Mateos E, Carratalá J, Pérez-Simón JA, Cisneros JM.

Vol: Lancet Haematol Revista Internacional
Revista Internacional

P-Sulfocalix[6]arene as Nanocarrier for Controlled Delivery of Doxorubicin

Ostos FJ, Lebrón JA, Moyá ML, López-López M, Sánchez A, Clavero A, García-Calderón CB, Rosado IV, López-Cornejo P.

Vol: Chem Asian J. Revista Internacional
Revista Internacional

Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab.

García-Guerrero E, Gogishvili T, Danhof S, Schreder M, Pallaud C, Pérez-Simón JA, Einsele H, Hudecek M.

Vol: Blood. Revista Internacional
Revista Internacional

Platelet phagocytosis by granulopoietic precursors in a myelodysplastic syndrome overexpressing the P-selectin gene.

Morales-Camacho RM, Serrano-Chacón MD, Prats-Martín C, Vargas MT, Bernal R, Burillo-Sanz S.

Vol: Br J Haematol. Revista Internacional
Revista Internacional

Presence of acute and chronic renal failure in patients with paroxysmal nocturnal hemoglobinuria: results of a retrospective analysis from the Spanish PNH Registry

Villegas A, Núñez R, Gaya A, Cuevas-Ruiz MV, Bosch JM, Carral A, Arrizabalaga B, Gómez-Roncero MI, Mora A, Bravo P, Lavilla E, Monteserín C, Hernández B, Martínez-Barranco P, Jarque I, Urquía MA, García-Donas G, Brunet S, González FA, Urbano Á.

Vol: Ann Hematol Revista Internacional
Revista Internacional

RUNX1 amplification in AML with myelodysplasia-related changes and ring 21 chromosomes.

Burillo-Sanz S, Vargas MT, Morales-Camacho RM, Caballero-Velázquez T, Sánchez J, García-Lozano JR, Pérez de Soto I, Prats-Martín C, Bernal R, Pérez-Simón JA.

Vol: Hematol Oncol Revista Internacional
Revista Internacional

Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia.

Cornely OA, Leguay T, Maertens J, Vehreschild MJGT, Anagnostopoulos A, Castagnola C, Verga L, Rieger C, Kondakci M, Härter G, Duarte RF, Allione B, Cordonnier C, Heussel CP, Morrissey CO, Agrawal SG, Donnelly JP, Bresnik M, Hawkins MJ, Garner W, Gökbuget N, AmBiGuard Study Group.

Vol: J Antimicrob Chemother. Revista Internacional
Revista Internacional

Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate

Merlo A, Bernardo-Castiñeira C, Sáenz-de-Santa-María I, Pitiot AS, Balbín M, Astudillo A, Valdés N, Scola B, Del Toro R, Méndez-Ferrer S, Piruat JI, Suarez C, Chiara MD.

Vol: Oncotarget Revista Internacional
Revista Internacional

Sdhd ablation promotes thyroid tumorigenesis by inducing a stem-like phenotype.

Ashtekar A, Huk D, Magner A, La Perle K, Zhang X, Piruat JI, López-Barneo J, Jhiang SM, Kirschner LS.

Vol: Endocr Relat Cancer. Revista Internacional
Revista Internacional

Tacrolimus plus sirolimus with or without ATG as GVHD prophylaxis in HLA-mismatched unrelated donor allogeneic stem cell transplantation.

Kharfan-Dabaja MA, Parody R, Perkins J, López-Godino O, López-Corral L, Vázquez L, Caballero D, Falantes J, Shapiro J, Ortí G, Barba P, Valcárcel D, Esquirol A, Martino R, Piñana JL, Solano C, Tsalatsanis A, Pidala J, Anasetti C, Pérez-Simón JA. B

Vol: one Marrow Transplant Revista Internacional
Revista Internacional

The incorporation of comorbidities in the prognostication of patients with lower-risk myelodysplastic syndrome.

Falantes JF, Márquez-Malaver FJ, Knight T, Calderón-Cabrera C, Martino ML, González J, Montero I, Espigado I, Pérez-Simón JA.

Vol: Leuk Lymphoma. Revista Internacional
Revista Internacional

Treatment options for relapse after autograft in multiple myeloma - report from an EBMT educational meeting.

Garderet L, Cook G, Auner HW, Bruno B, Lokhorst H, Pérez-Simón JA, Sahebi F, Scheid C, Morris C, van Biezen A, Sobh M, Michallet M, Gahrton G, Schönland S, Kröger N. .

Vol: Leuk Lymphoma Revista Internacional
2012
2011
Revista Internacional

Effect of vitamin D treatment in chronic GVHD.

Silva F, Pérez-Simón JA, Caballero-Velazquez T, Sánchez-Guijo FM, Villanueva-Gómez F, Vazquez L, Del Cañizo C, Caballero D, San Miguel J.

Vol: Bone Marrow Transplant. 2011 Jan 17. [Epub ahead of print] Revista Internacional
Revista Internacional

Limbus damage in ocular graft-versus-host disease.

Pérez RL, Pérez-Simón JA, Caballero-Velazquez T, Flores T, Carrancio S, Herrero C, Blanco B, Gutierrez-Cosio S, Cañete-Campos C, Cruz González F, San-Miguel JF, Hernández-Galilea E, Sánchez-Abarca I.

Vol: Biol Blood Marrow Transplant. 2011 Feb;17(2):270-3. Revista Internacional
2010
Revista Internacional

A molecular risk score based on 4 functional pathways for advanced classical Hodgkin lymphoma.

Sánchez-Espiridión B, Montalbán C, López A, Menárguez J, Sabín P, Ruiz-Marcellán C, Lopez A, Ramos R, Rodríguez J, Cánovas A, Camarero C, Canales M, Alves J, Arranz R, Acevedo A, Salar A, Serrano S, Bas A, Moraleda JM, Sánchez-Godoy P, Burgos F, Rayón C, Fresno MF, Laraña JG, García-Cosío M, Santonja C, López JL, Llanos M, Mollejo M, González-Carrero J, Marín A, Forteza J, García-Sanz R, Tomás JF, Morente MM, Piris MA, García JF; Spanish Hodgkin Lymphoma Study Group.

Vol: Blood. 2010 Aug 26;116(8):e12-7. Revista Internacional
Revista Internacional

European Myeloma Network: the 3rd trialist forum consensus statement from the European experts meeting on multiple myeloma.

Engelhardt M, Udi J, Kleber M, Spencer A, Rocci A, Knop S, Bruno B, Bringhen S, Pérez-Simón JA, Zweegman S, Driessen C, Patriarca F, Gramatzki M, Terpos E, Sezer O, Kropff M, Straka C, Johnsen HE, Waage A, Boegsted M, Lokhorst H, Hájek R, Morgan G, Boccadoro M, Ludwig H, Cavo M, Polliack A, Sonneveld P, Einsele H, Palumbo A.

Vol: Leuk Lymphoma. 2010 Nov;51(11):2006-11. Revista Internacional
Revista Internacional

Helicobacter pylori Infection and Graft-versus-Host Disease.

Velasco Guardado A, López-Corral L, Pérez-Simón JA, Caballero-Velázquez T, Flores Corral T, Caballero Barrigón D, Rodríguez Pérez A.

Vol: Biol Blood Marrow Transplant. 2010 Nov 18. [Epub ahead of print] Revista Internacional
2009
Revista Internacional

Treatment with bortezomib of human CD4+ T cells preserves natural regulatory T cells and allows the emergence of a distinct suppressor T-cell population.

Blanco B, Pérez-Simón JA, Sánchez-Abarca LI, Caballero-Velazquez T, Gutierrez-Cossío S, Hernández-Campo P, Díez-Campelo M, Herrero-Sanchez C, Rodriguez-Serrano C, Santamaría C, Sánchez-Guijo FM, Del Cañizo C, San Miguel JF.

Vol: Haematologica. 2009 Jul;94(7):975-83. Revista Internacional
2008
Revista Internacional

A prospective pethema study of tandem autologous transplantation versus autograft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma.

Rosiñol L, Pérez-Simón JA, Sureda A, de la Rubia J, de Arriba F, Lahuerta JJ, González JD, Díaz-Mediavilla J, Hernández B, García-Frade J, Carrera D, León A, Hernández M, Abellán PF, Bergua JM, San Miguel J, Bladé J; Programa para el Estudio y la Terapéutica de las Hemopatías Malignas y Grupo Español de Mieloma (PETHEMA/GEM).

Vol: Blood. 2008 Nov 1;112(9):3591-3. Revista Internacional
Revista Internacional

Prognostic factors of chronic graft-versus-host disease following allogeneic peripheral blood stem cell transplantation: the national institutes health scale plus the type of onset can predict survival rates and the duration of immunosuppressive therapy.

Pérez-Simón JA, Encinas C, Silva F, Arcos MJ, Díez-Campelo M, Sánchez-Guijo FM, Colado E, Martín J, Vazquez L, del Cañizo C, Caballero D, San Miguel J.

Vol: Biol Blood Marrow Transplant. 2008 Oct;14(10):1163-71. Revista Internacional
Revista Internacional

Reduced-intensity conditioning allogeneic transplantation from unrelated donors: evaluation of mycophenolate mofetil plus cyclosporin A as graft-versus-host disease prophylaxis.

Pérez-Simón JA, Martino R, Caballero D, Valcarcel D, Rebollo N, de la Cámara R, de Oteiza JP, Heras I, Calvo MV, Sierra J, San Miguel JF; Grupo Español de Trasplante Hematopoyético (GETH).

Vol: Biol Blood Marrow Transplant. 2008 Jun;14(6):664-71. Revista Internacional
Revista Internacional

Sustained remissions of high-risk acute myeloid leukemia and myelodysplastic syndrome after reduced-intensity conditioning allogeneic hematopoietic transplantation: chronic graft-versus-host disease is the strongest factor improving survival.

Valcárcel D, Martino R, Caballero D, Martin J, Ferra C, Nieto JB, Sampol A, Bernal MT, Piñana JL, Vazquez L, Ribera JM, Besalduch J, Moraleda JM, Carrera D, Brunet MS, Perez-Simón JA, Sierra J.

Vol: J Clin Oncol. 2008 Feb 1;26(4):577-84. Revista Internacional
2007
2006
Revista Internacional

Combined vaccination with idiotype-pulsed allogeneic dendritic cells and soluble protein idiotype for multiple myeloma patients relapsing after reduced-intensity conditioning allogeneic stem cell transplantation.

Bendandi M, Rodríguez-Calvillo M, Inogés S, López-Díaz de Cerio A, Pérez-Simón JA, Rodríguez-Caballero A, García-Montero A, Almeida J, Zabalegui N, Giraldo P, San Miguel J, Orfao A.

Vol: Leuk Lymphoma. 2006 Jan;47(1):29-37. Revista Internacional
Revista Internacional

Reduced intensity conditioning allogeneic transplantation is associated with a high incidence of extramedullary relapses in multiple myeloma patients.

Pérez-Simón JA, Sureda A, Fernández-Aviles F, Sampol A, Cabrera JR, Caballero D, Martino R, Petit J, Tomás JF, Moraleda JM, Alegre A, Cañizo C, Brunet S, Rosiñol L, Lahuerta J, Díez-Martín JL, León A, García A, Vazquez L, Sierra J, San Miguel JF; Grupo Español de Mieloma.

Vol: Leukemia. 2006 Mar;20(3):542-5. Revista Internacional
Revista Internacional

Remarkable activity of novel agents bortezomib and thalidomide in patients not responding to donor lymphocyte infusions following nonmyeloablative allogeneic stem cell transplantation in multiple myeloma.

van de Donk NW, Kröger N, Hegenbart U, Corradini P, San Miguel JF, Goldschmidt H, Perez-Simon JA, Zijlmans M, Raymakers RA, Montefusco V, Ayuk FA, van Oers MH, Nagler A, Verdonck LF, Lokhorst HM.

Vol: Blood. 2006 Apr 15;107(8):3415-6. Revista Internacional