Expresión Génica

Genome-scale mapping of DNA damage suppressors through phenotypic CRISPR-Cas9 screens

Enhanced gene regulation by cooperation between mRNA decay and gene transcription

Nucleo-cytoplasmic shuttling of RNA-binding factors: mRNA buffering and beyond

Nuclear ingression of cytoplasmic bodies accompanies a boost in autophagy

Quantitative analysis of protein-RNA interactions in fission yeast

The total mRNA concentration buffering system in yeast is global rather than gene-specific

Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration

Human prefoldin modulates co-transcriptional pre-mRNA splicing

Transcriptional Run-on: Measuring Nascent Transcription at Specific Genomic Sites in Yeast

Cell volume homeostatically controls the rDNA repeat copy number and rRNA synthesis rate in yeast

Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity

Overexpression of Canonical Prefoldin Associates with the Risk of Mortality and Metastasis in Non-Small Cell Lung Cancer

DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II.

FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress.

Homeostasis in the Central Dogma of molecular biology: the importance of mRNA instability.

Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae.

The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4.

Feedback regulation of ribosome assembly.

High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1

Rpb5 modulates the RNA polymerase II transition from initiation to elongation by influencing Spt5 association and backtracking.

Asymmetric cell division requires specific mechanisms for adjusting global transcription

Placeholder factors in ribosome biogenesis: please, pave my way.

Regulation of transcription elongation in response to osmostress.

Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning.

TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.

The ribosome assembly gene network is controlled by the feedback regulation of transcription elongation.

Growth rate controls mRNA turnover in steady and non-steady states.

Prefoldins

The cellular growth rate controls overall mRNA turnover, and modulates either transcription or degradation rates of particular gene regulons.

The importance of controlling mRNA turnover during cell proliferation.

Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.

Cis- and trans-regulatory mechanisms of gene expression in the ASJ sensory neuron of Caenorhabditis elegans.

H3K4 monomethylation dictates nucleosome dynamics and chromatin remodeling at stress-responsive genes

Cytoplasmic 5'-3' exonuclease Xrn1p is also a genome-wide transcription factor in yeast.

Flow cytometry of microencapsulated colonies for genetics analysis of filamentous fungi.

Nuclear functions of prefoldin

RNA polymerase II-dependent transcription in fungi and its interplay with mRNA decay.

The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription.

Balanced production of ribosome components is required for proper G1/S transition in Saccharomyces cerevisiae.

Eukaryotic mRNA decay: methodologies, pathways, and links to other stages of gene expression.

External conditions inversely change the RNA polymerase II elongation rate and density in yeast.

Gene expresión is circular: factors for mRNA degradation also foster mRNA synthesis.

The Prefoldin Complex Regulates Chromatin Dynamics during Transcription Elongation.

What do you mean by transcription rate?: the conceptual difference between nascent transcription rate and mRNA synthesis rate is essential for the proper understanding of transcriptomic analyses.