Enfermedades infecciosas y del sistema inmunitario

Infecciones víricas y en pacientes inmunodeprimidos

Elisa Cordero Matía
Elisa Cordero Matía
Javier Sánchez Céspedes
Javier Sánchez Céspedes

Elisa Cordero Matía

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  1. Miembros del grupo
  2. Áreas de trabajo
  3. Publicaciones

Grupo: Infecciones víricas y en pacientes inmunodeprimidos

Directorio
Miembros del grupo Infecciones víricas y en pacientes inmunodeprimidos
  • Aguilar Guisado, Manuela.Doctora en Medicina. FEA HUVR
  • Balsera Manzanero, María.Graduada en Biología. Técnico de apoyo
  • Carretero Ledesma, Marta.Doctorada en Biomedicina. Posdoctoral
  • Cordero Matía, Elisa.Doctora en Medicina. FEA HUVR - Profesora Titular US
  • Gálvez Benítez, Lydia.Graduada en Medicina. MIR Servicio de Microbiología HUVR
  • Martín Escolano, Javier.Graduado en Biología. PFIS
  • Pachón Díaz, Jerónimo.Doctor en Medicina. Profesor Emérito US
  • Roca Oporto, Cristina.Graduada en Medicina. FEA HUVR
  • Rodríguez Hernández, Mª Jesús.Doctorada en Medicina. FEA HUVR
  • Ruiz Molina, Ana María.Graduada en Biotecnología. Empleo Joven
  • Salto Alejandre, Sonsoles.Graduada en Medicina. MIR HUVR
  • Sánchez Céspedes, Javier.Doctor en Biología. Nicolás Monardes - UGC Enfermedades Infecciosas

Áreas de trabajo

Líneas de Investigación: 

a. Infecciones víricas con potencial pandémico y otras infecciones víricas en pacientes inmunodeprimidos

  • Infecciones relacionadas con la gripe
  • Infecciones relacionadas con COVID-19
  • Desarrollo de moléculas antivirales


b. Infecciones bacterianas en pacientes inmunodeprimidos

Para el desarrollo de las líneas de investigación disponemos de las diferentes técnicas en: 

a. Investigación Clínica: 

  • Diseño y desarrollo de estudios de cohortes
  • Diseño y desarrollo de estudios de casos y controles
  • Diseño y desarrollo de ensayos clínicos aleatorizados
  • Análisis de datos con técnicas avanzadas

b. Biología molecular y celular para el estudio de infecciones virales y bacterianas

c. Respuesta inmunitaria innata, celular y humoral

d. Modelos animales de infección experimental

 

Revistas Internacionales
Guisado-Gil AB, Aguilar-Guisado M, Peñalva G, Lepe JA, Espigado I, Rodríguez-Arbolí E, González-Campos J, Rodríguez-Torres N, Montero-Cuadrado MI, Falantes-González JF, Reguera-Ortega JL, Gil-Navarro MV, Molina J, Pérez-Simón JA, Cisneros JM
Long-Term Impact of an Educational Antimicrobial Stewardship Program on Management of Patients with Hematological Diseases.
Antibiotics (Basel)
PubMed
Sonsoles Salto-Alejandre, Silvia Jiménez-Jorge, Nuria Sabé, Antonio Ramos-Martínez, Laura Linares, Maricela Valerio, Pilar Martín-Dávila, Mario Fernández-Ruiz, María Carmen Fariñas, Marino Blanes-Juliá, Elisa Vidal, Zaira R. Palacios-Baena, Román Hernández-Gallego, Jordi Carratalá, Jorge Calderón-Parra, María Ángeles Marcos, Patricia Muñoz, Jesús Fortún-Abete, José María Aguado, Francisco Arnaiz-Revillas, Rosa Blanes-Hernández, Julián de la Torre-Cisneros, Luis E. López-Cortés, Elena García de Vinuesa-Calvo, Clara M. Rosso, Jerónimo Pachón, Javier Sánchez-Céspedes, Elisa Cordero, on behalf of The COVIDSOT Working Team (José Miguel Cisneros, Judith Berastegui-Cabrera).
Risk factors for unfavorable outcome and impact of early post-transplant infection in solid organ recipients with COVID-19: A prospective multicenter cohort study.
PloS One
Salto-Alejandre S, Roca-Oporto C, Martín-Gutiérrez G, Avilés MD, Gómez-González C, Navarro-Amuedo MD, Praena-Segovia J, Molina J, Paniagua-García M, García-Delgado H, Domínguez-Petit A, Pachón J, Cisneros JM
A quick prediction tool for unfavourable outcome in COVID-19 inpatients: Development and internal validation.
J Infect
PubMed
Xu J, Berastegui-Cabrera J, Carretero-Ledesma M, Chen H, Xue Y, Wold EA, Pachón J, Zhou J, Sánchez-Céspedes J
Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome
. Int J Mol Sci.
PubMed
Berastegui-Cabrera J, Salto-Alejandre S, Valerio M, Pérez-Palacios P, Revillas FAL, Abelenda-Alonso G, Oteo-Revuelta JA, Carretero-Ledesma M, Muñoz P, Pascual Á, Gozalo M, Rombauts A, Alba J, García-Díaz E, Rodríguez-Ferrero ML, Valiente A, Fariñas MC, Carratalà J, Santibáñez S, Camacho-Martínez P, Pachón J, Cisneros JM, Cordero E, Sánchez-Céspedes J.
SARS-CoV-2 RNAemia is associated with severe chronic underlying diseases but not with nasopharyngeal viral load.
J Infect
PubMed
Cebrero-Cangueiro T, Labrador-Herrera G, Pascual Á, Díaz C, Rodríguez-Baño J, Pachón J, Del Palacio JP, Pachón-Ibáñez ME*, Conejo MC.
Efficacy of Fosfomycin and Its Combination With Aminoglycosides in an Experimental Sepsis Model by Carbapenemase-Producing <i>Klebsiella pneumoniae</i> Clinical Strains
Front Med (Lausanne).
PubMed
Fontserè S, Infante-Domínguez C, Suárez-Benjumea A, Suñer-Poblet M, González-Corvillo C, Martín-Gutiérrez G, Bernal G, Pachón J, Pachón-Ibáñez ME, Cordero E
Impact of Treating Asymptomatic Bacteriuria in Kidney Transplant Recipients: A Prospective Cohort Study.
Antibiotics (Basel).
PubMed
. Cebrero-Cangueiro T, Nordmann P, Carretero-Ledesma M, Pachón J, Pachón-Ibáñez ME.
Efficacy of dual carbapenem treatment in a murine sepsis model of infection due to carbapenemase-producing Acinetobacter baumannii.
J Antimicrob Chemother
PubMed
Miró-Canturri A, Ayerbe-Algaba R, Vila-Domínguez A, Jiménez-Mejías ME, Pachón J, Smani Y.
Repurposing of the Tamoxifen Metabolites to Combat Infections by Multidrug-Resistant Gram-Negative Bacilli.
Antibiotics (Basel).
PubMed
Miró-Canturri A, Ayerbe-Algaba R, Jiménez-Mejías ME, Pachón J, Smani Y
Efficacy of Lysophosphatidylcholine as Direct Treatment in Combination with Colistin against Acinetobacter baumannii in Murine Severe Infections Models.
Antibiotics (Basel)
PubMed
Ayerbe-Algaba R, Bayó N, Verdú E, Parra-Millán R, Seco J, Teixidó M, Pachón J, Giralt E, Smani Y.
AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections.
Front Microbiol.
PubMed
Javier Sánchez-Céspedes, José Antonio Marrugal-Lorenzo, Cecilia Martín-Gandul, Nancy Rodríguez-Torres, Enrique Montero-Mateos, Ana Serna-Gallego, Virginia Escamilla-Gómez, Laura Merino, Ildefonso Espigado, Jerónimo Pachón, José Antonio Pérez-Simón, Manuela Aguilar-Guisado
T-cells Immune Response Controls the High Incidence of Adenovirus Infection in Adult Allogenic Hematopoietic Transplantation Recipients
. Haematologica
PubMed
Rodríguez-Baño J, Pachón J, Carratalà J, Ryan P, Jarrín I, et al.
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19).
Clin Microbiol Infect
PubMed
Gutiérrez-Gutiérrez B, Del Toro MD, Borobia AM, Carcas A, Jarrín I, Yllescas M, Ryan P, Pachón J, Carratalà J, Berenguer J, Arribas JR, Rodríguez-Baño J; REIPI-SEIMC COVID-19 group and COVID@HULP groups
Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19: a multicentre cohort study.
Lancet Infect Dis
PubMed
Berenguer J, Borobia AM, Ryan P, Rodríguez-Baño J, Bellón JM, Jarrín I, Carratalà J, Pachón J, Carcas AJ, Yllescas M, Arribas JR; COVID-19@Spain and COVID@HULP Study Groups.
Development and validation of a prediction model for 30-day mortality in hospitalised patients with COVID-19: the COVID-19 SEIMC score.
Thorax
PubMed
A. Miró-Canturri; R. Ayerbe-Algaba; R. del Toro; ME. Jiménez-Mejías; J. Pachón; Y. Smani.
Potential Tamoxifen Repurposing to Combat Infections by Multidrug-Resistant Gram-Negative Bacilli.
Pharmaceuticals
R Parra-Millán; ME Jiménez-Mejías; R Ayerbe-Algaba; J Domínguez-Herrera; C Díaz; J Pérez del Palacio; J Pachón; Y Smani
. Impact of the immune response modification by lysophosphatydylcholine in the efficacy of antibiotic therapy of experimental models of peritoneal sepsis and pneumonia by Pseudomonas aeruginosa: LPC therapeutic effect in combined therapy.
Enfermedades Infecciosas y Microbiologiía Clínica. Madrid(España):
Los-Arcos, I; Iacoboni, G; Aguilar-Guisado, M; Alsina-Manrique, L; de Heredia, CD; Fortuny-Guasch, C; Garcia-Cadenas, I; Garcia-Vidal, C; Gonzalez-Vicent, M; Hernani, R; Kwon, M; Machado, M; Martinez-Gomez, X; Maldonado, VO; Pla, CP; Pinana, JL; Pomar, V; Reguera-Ortega, JL; Salavert, M; Soler-Palacin, P; Vazquez-Lopez, L; Barba, P; Ruiz-Camps, I
Recommendations for screening, monitoring, prevention, and prophylaxis of infections in adult and pediatric patients receiving CAR T-cell therapy: a position paper
INFECTION
Mazzotta, S; Cebrero-Cangueiro, T; Frattaruolo, L; Vega-Holm, M; Carretero-Ledesma, M; Sanchez-Cespedes, J; Cappello, AR; Aiello, F; Pachon, J; Vega-Perez, JM; Iglesias-Guerra, F; Pachon-Ibanez, ME
Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Aranzana-Climent, V; Buyck, JM; Smani, Y; Pachon-Diaz, J; Marchand, S; Couet, W; Gregoire, N
Semi-mechanistic PK/PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii
CLINICAL MICROBIOLOGY AND INFECTION
Berenguer, J; Ryan, P; Rodriguez-Bano, J; Jarrin, I; Carratala, J; Pachon, J; Yllescas, M; Arriba, JR
Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain
CLINICAL MICROBIOLOGY AND INFECTION
Rodriguez-Villodres, A; Lepe, JA; Blazquez, J; Aznar, J
Effect of subinhibitory concentrations of ampicillin on Listeria monocytogenes
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Cordero, E; Goycochea-Valdivia, W; Mendez-Echevarria, A; Allende, LM; Alsina, L; Garcia-Morato, MB; Gil-Herrera, J; Gudiol, C; Len-Abad, O; Lopez-Medrano, F; Moreno-Perez, D; Munoz, P; Olbrich, P; Sanchez-Ramon, S; Soler-Palacin, P; Cros, CA; Arostegui, JI; Serra, IB; Carbone, J; Fortun, J; Gonzalez-Granado, LI; Lopez-Granados, E; Lucena, JM; Parody, R; Ramakers, J; Regueiro, JR; Riviere, JG; Roca-Oporto, C; Pena, RR; Santos-Perez, JL; Rodriguez-Gallego, C; Neth, O
Executive Summary of the Consensus Document on the Diagnosis and Management of Patients with Primary Immunodeficiencies
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Gudiol, C; Aguilar-Guisado, M; Azanza, JR; Candel, FJ; Canton, R; Carratala, J; Garcia-Vidal, C; Jarque, I; Lizasoain, M; Gil-Bermejo, JM; Ruiz-Camps, I; Sanchez-Ortega, I; Solano, C; Suarez-Lledo, M; Vazquez, L; de la Camara, R
Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiolog
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Mazzotta, S; Marrugal-Lorenzo, JA; Vega-Holm, M; Serna-Gallego, A; Alvarez-Vidal, J; Berastegui-Cabrera, J; del Palacio, JP; Diaz, C; Aiello, F; Pachon, J; Iglesias-Guerra, F; Vega-Perez, JM; Sanchez-Cespedes, J
Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Aguilar-Guisado, M; Marrugal-Lorenzo, JA; Berastegui-Cabrera, J; Merino, L; Pachon, J; Sanchez-Cespedes, J
In vitro co-infection by cytomegalovirus improves the antiviral activity of ganciclovir against human adenovirus
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Cordero, E; Goycochea-Valdivia, W; Mendez-Echevarria, A; Allende, LM; Alsina, L; Garcia-Morato, MB; Gil-Herrera, J; Gudiol, C; Len-Abad, O; Lopez-Medrano, F; Moreno-Perez, D; Munoz, P; Olbrich, P; Sanchez-Ramon, S; Soler-Palacin, P; Cros, CA; Arostegui, JI; Serra, IB; Carbone, J; Fortun, J; Gonzalez-Granado, LI; Lopez-Granados, E; Lucena, JM; Parody, R; Ramakers, J; Regueiro, JR; Riviere, JG; Roca-Oporto, C; Pena, RR; Santos-Perez, JL; Rodriguez-Gallego, C; Neth, O
Executive Summary of the Consensus Document on the Diagnosis and Management of Patients with Primary Immunodeficiencies
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
Alvarez-Marin, R; Navarro-Amuedo, D; Gasch-Blasi, O; Rodriguez-Martinez, JM; Calvo-Montes, J; Lara-Contreras, R; Lepe-Jimenez, JA; Tubau-Quintano, F; Cano-Garcia, ME; Rodriguez-Lopez, F; Rodriguez-Bano, J; Pujol-Rojo, M; Torre-Cisneros, J; Martinez-Martinez, L; Pascual-Hernandez, A; Jimenez-Mejias, ME; Alvarez-Martinez, R; Calvo, J; de Cueto, M; Cano, ME; de Teran, TD; Dominguez-Herrera, J; Mazarrasa, CF; Gasch, O; Martin-Gandul, C; Diaz, JP; Pujol, M; Puppo, I; Smani, Y; Tubau, F; de la Torre-Cisneros, J
A prospective, multicenter case control study of risk factors for acquisition and mortality in Enterobacter species bacteremia
JOURNAL OF INFECTION
Pulido, MR; Garcia-Quintanilla, M; Pachon, J; McConnell, MJ
A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection
VACCINE
Xu, JM; Berastegui-Cabrera, J; Ye, N; Carretero-Ledesma, M; Pachon-Diaz, J; Chen, HY; Pachon-Ibanez, ME; Sanchez-Cespedes, J; Zhou, J
Discovery of Novel Substituted N-(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
Xu, JM; Berastegui-Cabrera, J; Chen, HY; Pachon, J; Zhou, J; Sanchez-Cespedes, J
Structure-Activity Relationship Studies on Diversified Salicylamide Derivatives as Potent Inhibitors of Human Adenovirus Infection
JOURNAL OF MEDICINAL CHEMISTRY
Labrador-Herrera, G; Perez-Pulido, AJ; Alvarez-Marin, R; Casimiro-Soriguer, CS; Cebrero-Cangueiro, T; Moran-Barrio, J; Pachon, J; Viale, AM; Pachon-Ibanez, ME
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii
VIRULENCE
Gil-Marques, ML; Herrera, GL; Canturri, AM; Pachon, J; Smani, Y; Pachon-Ibanez, ME
Role of PstS in the Pathogenesis of Acinetobacter baumannii Under Microaerobiosis and Normoxia
JOURNAL OF INFECTIOUS DISEASES
Miro-Canturri, A; Ayerbe-Algaba, R; Villodres, AR; Pachon, J; Smani, Y
Repositioning rafoxanide to treat Gram-negative bacilli infections
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Rodriguez-Villodres, N; Gil-Marques, ML; Alvarez-Marin, R; Bonnin, RA; Pachon-Ibanez, ME; Aguilar-Guisado, M; Naas, T; Aznar, J; Pachon, J; Lepe, JA; Smani, Y
Extended-spectrum resistance to beta-lactams/beta-lactamase inhibitors (ESRI) evolved from low-level resistant Escherichia coli
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Milanes-Guisado, Y; Gutierrez-Valencia, A; Munoz-Pichardo, JM; Rivero, A; Trujillo-Rodriguez, M; Ruiz-Mateos, E; Espinosa, N; Roca-Oporto, C; Viciana, P; Lopez-Cortes, LF
Is immune recovery different depending on the use of integrase strand transfer inhibitor-, non-nucleoside reverse transcriptase- or boosted protease inhibitor-based regimens in antiretroviral-naive HIV-infected patients?
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Cardozo, C; Cuervo, G; Salavert, M; Merino, P; Gioia, F; Fernandez-Ruiz, M; Lopez-Cortes, LE; Escola-Verge, L; Montejo, M; Munoz, P; Aguilar-Guisado, M; Puerta-Alcalde, P; Tasias, M; Ruiz-Gaitan, A; Gonzalez, F; Puig-Asensio, M; Vena, A; Marco, F; Peman, J; Fortun, J; Aguado, JM; Almirante, B; Soriano, A; Carratala, J; Garcia-Vidal, C
An evidence-based bundle improves the quality of care and outcomes of patients with candidaemia
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Cornely, OA; Cisneros, JM; Torre-Cisneros, J; Rodriguez-Hernandez, MJ; Tallon-Aguilar, L; Calbo, E; Horcajada, JP; Queckenberg, C; Zettelmeyer, U; Arenz, D; Rosso-Fernandez, CM; Jimenez-Jorge, S; Turner, G; Raber, S; O'Brien, S; Luckey, A
Pharmacokinetics and safety of aztreonam/avibactam for the treatment of complicated intra-abdominal infections in hospitalized adults: results from the REJUVENATE study
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Vitalle, J; Tarancon-Diez, L; Jimenez-Leon, MR; Terren, I; Orrantia, A; Roca-Oporto, C; Lopez-Cortes, L; Ruiz-Mateos, E; Zenarruzabeitia, O; Borrego, F
CD300a identifies a CD4(+)memory T cell subset with a higher susceptibility to HIV-1 infection
AIDS
De Pablo-Bernal, RS; Jimenez-Leon, MR; Tarancon-Diez, L; Gutierrez-Valencia, A; Serna-Gallego, A; Trujillo-Rodriguez, M; Alvarez-Rios, AI; Milanes-Guisado, Y; Espinosa, N; Roca-Oporto, C; Viciana, P; Lopez-Cortes, LF; Ruiz-Mateos, E
Modulation of Monocyte Activation and Function during Direct Antiviral Agent Treatment in Patients Coinfected with HIV and Hepatitis C Virus
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Gudiol, C; Arnan, M; Aguilar-Guisado, M; Royo-Cebrecos, C; Sanchez-Ortega, I; Montero, I; Martin-Gandul, C; Laporte-Amargis, J; Albasanz-Puig, A; Nicolae, S; Perayre, M; Berbel, D; Tebe, C; Riera, J; Sureda, A; Cisneros, JM; Carratala, J
A Randomized, Double-Blind, Placebo-Controlled Trial (TAURCAT Study) of Citrate Lock Solution for Prevention of Endoluminal Central Venous Catheter Infection in Neutropenic Hematological Patients
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Bassetti, M; Vena, A; Meroi, M; Cardozo, C; Cuervo, G; Giacobbe, DR; Salavert, M; Merino, P; Gioia, F; Fernandez-Ruiz, M; Lopez-Cortes, LE; Almirante, B; Escola-Verge, L; Montejo, M; Aguilar-Guisado, M; Puerta-Alcalde, P; Tasias, M; Ruiz-Gaitan, A; Gonzalez, F; Puig-Asensio, M; Marco, F; Peman, J; Fortun, J; Aguado, JM; Soriano, A; Carratala, J; Garcia-Vidal, C; Valerio, M; Sartor, A; Bouza, E; Munoz, P
Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts
CRITICAL CARE
Cordero, E; Bulnes-Ramos, A; Aguilar-Guisado, M; Escribano, FG; Olivas, I; Torre-Cisneros, J; Gavalda, J; Aydillo, T; Moreno, A; Montejo, M; Farinas, MC; Carratala, J; Munoz, P; Blanes, M; Fortun, J; Suarez-Benjumea, A; Lopez-Medrano, F; Roca, C; Lara, R; Perez-Romero, P
Effect of Influenza Vaccination Inducing Antibody Mediated Rejection in Solid Organ Transplant Recipients
FRONTIERS IN IMMUNOLOGY
Dominguez, AV; Algaba, RA; Canturri, AM; Villodres, AR; Smani, Y
Antibacterial Activity of Colloidal Silver against Gram-Negative and Gram-Positive Bacteria
ANTIBIOTICS-BASEL
Guisado-Gil, AB; Infante-Dominguez, C; Penalva, G; Praena, J; Roca, C; Navarro-Amuedo, MD; Aguilar-Guisado, M; Espinosa-Aguilera, N; Poyato-Borrego, M; Romero-Rodriguez, N; Aldabo, T; Salto-Alejandre, S; de Pipaon, MRP; Lepe, JA; Martin-Gutierrez, G; Gil-Navarro, MV; Molina, J; Pachon, J; Cisneros, JM
Impact of the COVID-19 Pandemic on Antimicrobial Consumption and Hospital-Acquired Candidemia and Multidrug-Resistant Bloodstream Infections
ANTIBIOTICS-BASEL
Herrera-Espejo, S; Cebrero-Cangueiro, T; Labrador-Herrera, G; Pachon, J; Pachon-Ibanez, ME; Alvarez-Marin, R
In Vitro Activity of Pentamidine Alone and in Combination with Antibiotics against Multidrug-Resistant Clinical Pseudomonas aeruginosa Strains
ANTIBIOTICS-BASEL
Pech-Puch, D; Berastegui-Cabrera, J; Perez-Povedano, M; Villegas-Hernandez, H; Guillen-Hernandez, S; Cautain, B; Reyes, F; Pachon, J; Gomez, P; Rodriguez, J; Jimenez, C; Sanchez-Cespedes, J
Antiviral and Antiproliferative Potential of Marine Organisms From the Yucatan Peninsula, Mexico
FRONTIERS IN MARINE SCIENCE
HIRZEL C, FERREIRA VH, L’HUILLIER AG, HOSCHLER K, CORDERO E, LIMAYE AP, ENGLUND JA, REID G, HUMAR A, KUMAR D, INFLUENZAIN TRANSPLANTSTUDY GROUP
HUMORAL RESPONSE TO NATURAL INFLUENZA INFECTION IN SOLID ORGAN TRANSPLANT RECIPIENTS.
AM J TRANSPLANT
PEREZ-NADALES E, GUTIERREZ-GUTIERREZ B, NATERA AM, ABDALA E, REINA MAGALHÃES M, MULARONI A, MONACO F, CAMERA PIERROTTI L, PINHEIRO FREIRE M, IYER RN, MEHTA STEINKE S, GRAZIA CALVI E, TUMBARELLO M, FALCONE M, FERNANDEZ-RUIZ M, MARIA COSTA-MATEO J, RANA MM, MARA VAREJÃO STRABELLI T, PAUL M, CARMEN FARIÑAS M, CLEMENTE WT, ROILIDESE, MUÑOZ P, DEWISPELAEREL, LOECHES B, LOWMAN W, HOCK TAN B, ESCUDERO-SANCHEZ R, BODRO M, ANTONIO GROSSI P, SOLDANI F, GUNSEREN F, NESTOROVA N, PASCUAL A, MARTINEZ-MARTINEZ L, AGUADO JM, RODRIGUEZ-BAÑO J, TORRE-CISNEROSJ, REIPI/INCREMENT-SOT INVESTIGATORS
PREDICTORS OF MORTALITY IN SOLID ORGAN TRANSPLANT RECIPIENTS WITH BLOODSTREAM INFECTIONS DUE TO CARBAPENEMASE-PRODUCING ENTEROBACTERALES: THE IMPACT OF CYTOMEGALOVIRUS DISEASE AND LYMPHOPENIA
AM J TRANSPLANT
CISNEROS JM, ROSSO-FERNANDEZ CM, ROCA-OPORTO C, DE PASCALE G, JIMENEZ-JORGE S, FERNANDEZ-HINOJOSA E, MATTHAIOU DK, RAMIREZ P, DIAZ-MIGUEL RO, ESTELLA A, ANTONELLI M, DIMOPOULOS G, GARNACHO-MONTERO J, MAGIC BULLET WORKING GROUP WP1
COLISTIN VERSUS MEROPENEM IN THE EMPIRICAL TREATMENT OF VENTILATOR-ASSOCIATED PNEUMONIA (MAGIC BULLET STUDY): AN INVESTIGATOR-DRIVEN, OPEN-LABEL, RANDOMIZED, NONINFERIORITY CONTROLLED TRIAL
CRIT CARE.
MOLINA-ORTEGA A, MARTIN-GANDUL C, MENA-ROMO JD, RODRIGUEZ-HERNANDEZ MJ, SUÑER M, BERNAL C,SANCHEZ M,SANCHEZ-CESPEDESJ, PEREZ ROMERO P, CORDERO E
IMPACT OF PRETRANSPLANT CMV-SPECIFIC T-CELL IMMUNE RESPONSE IN THE CONTROL OF CMV INFECTION AFTER SOLID ORGAN TRANSPLANTATION: A PROSPECTIVE COHORT STUDY
CLIN MICROBIOL INFECT. 2
RODRIGUEZ-VILLODRES A, BONNIN RA, ORTIZ DE LA ROSA JM, ALVAREZ-MARIN R, NAAS T, AZNAR J, PACHON J, LEPEJA,SMANI
PHYLOGENY, RESISTOME, AND VIRULOME OF ESCHERICHIA COLI CAUSING BILIARY TRACT INFECTIONS.
J CLIN MED.
MOLINA J, NOGUER M, LEPE JA, PEREZ-MORENO MA, AGUILAR-GUISADO M, LASSO DE LAVEGA R, PEÑALVA G, CRESPO-RIVASJC, GIL-NAVARRO MV,SALVADOR J, CISNEROSJM
CLINICAL IMPACT OF AN EDUCATIONAL ANTIMICROBIAL STEWARDSHIP PROGRAM ASSOCIATED WITH INFECTIOUS DISEASES CONSULTATION TARGETING PATIENTS WITH CANCER: RESULTS OF A 9-YEAR QUASI-EXPERIMENTAL STUDY WITH AN INTERRUPTED TIME-SERIES ANALYSIS.
J INFECT
L’HUILLIER AG, FERREIRA VH, HIRZEL C, CORDERO E, LIMAYE AP, REID G, ENGLUND J, BLUMBERG E, KUMAR D, HUMAR A
CYTOKINE PROFILES AND SEVERITY OF INFLUENZA INFECTION IN TRANSPLANT RECIPIENTS.
J INFECT DIS.
MANGASEL, RUBIO A,ALVAREZ-MARIN R,LABRADOR-HERRERA G, PACHON J, PACHON-IBAÑEZ ME, DIVINAF, PEREZ-PULIDO AJ
PANGENOME OF ACINETOBACTER BAUMANNII UNCOVERS TWO GROUPS OF GENOMES, ONE OF THEM WITH GENES INVOLVED IN CRISPR/CAS DEFENCE SYSTEMS ASSOCIATED WITH THE ABSENCE OF PLASMIDSAND EXCLUSIVE GENESFOR BIOFILM FORMATION.
MICROB GENOM
AYERBE-ALGABA R, GIL-MARQUESML,MIRO-CANTURRIA, PARRA-MILLAN R, PACHON-IBAÑEZ ME, JIMENEZ-MEJIAS ME, PACHON J,S
THE ANTHELMINTIC OXYCLOZANIDE RESTORES THE ACTIVITY OF COLISTIN AGAINST COLISTIN-RESISTANT GRAM-NEGATIVE BACILLI.
INT J ANTIMICROB AGENTS.
MIRO-CANTURRIA,AYERBE-ALGABA R,SMANI
DRUG REPURPOSING FOR THE TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS.
FRONT MICROBIOL.
JIMENEZ-GONZALEZ V, OGALLA-GARCIA E, GARCIA-QUINTANILLA M, GARCIA-QUINTANILLA A
DECIPHERING GRINA/LIFEGUARD1: NUCLEAR LOCATION, CA2+ HOMEOSTASIS AND VESICLE TRANSPORT
INT J MOL SCI.
BLASCO L,AMBROAA, LOPEZ M, FERNANDEZ-GARCIAL, BLERIOT I, TRASTOY R, RAMOS-VIVASJ, COENYET,FERNANDEZ-CUENCAF,VILAJ,MARTINEZ-MARTINEZ L, RODRIGUEZ-BAÑO J, PASCUAL A, CISNEROS JM, PACHON J, BOU G, TOMAS M
COMBINED USE OF THE AB105-2ΦΔCI LYTIC MUTANT PHAGE AND DIFFERENT ANTIBIOTICS IN CLINICAL ISOLATES OF MULTI-RESISTANT ACINETOBACTER BAUMANNII.
MICROORGANISMS
MARRUGAL-LORENZO JA, SERNA-GALLEGO A, BERASTEGUI-CABRERA J, PACHON J, SANCHEZ-CESPEDESJ
REPOSITIONING SALICYLANILIDE ANTHELMINTIC DRUGS TO TREAT ADENOVIRUS INFECTIONS.
SCI REP.
GONZALEZ I, MOLINA-ORTEGAA, PEREZ-ROMERO P,ECHEVARRIAJE, HEL, TARRAGO D
VARICELLA-ZOSTER VIRUS CLADES CIRCULATING IN SPAIN OVER TWO DECADES.
J CLIN VIROL.
OPEZ-CORTESLE,AYERBE-GARCIA R, CARRASCO-HERNANDEZ L,FRAILE-RAMOSE, CARMONA-CABALLERO JM, QUINTANA-GALLEGO E, VALIDO-MORALES A, PRAENA J, PACHON-DIAZ J, DOMUS OPAT GROUP
OUTPATIENT PARENTERAL ANTIMICROBIAL TREATMENT FOR NON-CYSTIC FIBROSIS BRONCHIECTASIS EXACERBATIONS: A PROSPECTIVE MULTICENTRE OBSERVATIONAL COHORT STUDY.
RESPIRATION.
MITSUWAN W, JIMENEZ-MUNGUIA I, VISUTTHI M, SIANGLUM W, REIPI/GEIH STUDY GROUP, RODRIGUEZ-ORTEGA MJ,VORAVUTHIKUNCHAISP
RHODOMYRTONE DECREASES STAPHYLOCOCCUS AUREUS SIGB ACTIVITY DURING EXPONENTIALLY GROWING PHASE AND INHIBITS HAEMOLYTIC ACTIVITY WITHIN MEMBRANE VESICLES.
MICROB PATHOG.
ROCA-OPORTO C, CEBRERO-CANGUEIRO T, GIL-MARQUES ML, LABRADOR-HERRERA G, SMANI Y, GONZALEZ-RONCERO FM, MARIN LM, PACHON J, PACHON-IBAÑEZ ME, CORDERO E
PREVALENCE AND CLINICAL IMPACT OF STREPTOCOCCUS PNEUMONIAE NASOPHARYNGEAL CARRIAGE IN SOLID ORGAN TRANSPLANT RECIPIENTS
BMC INFECT DIS.
XU J, PACHON-IBAÑEZ ME, CEBRERO-CANGUEIRO T, CHEN H,SANCHEZ-CESPEDESJ, ZHOU J
DISCOVERY OF NICLOSAMIDE AND ITS O-ALKYLAMINO-TETHERED DERIVATIVES AS POTENT ANTIBACTERIAL AGENTS AGAINST CARBAPENEMASE-PRODUCING AND/OR COLISTIN RESISTANT ENTEROBACTERIACEAE ISOLATES
BIOORG MED CHEM LETT.
ESPINAL P, PANTEL A, ROLO D, MARTI S, LOPEZ-ROJAS R, SMANI Y, PACHON J, VILA J, LAVIGNE JP
RELATIONSHIP BETWEEN DIFFERENT RESISTANCE MECHANISMS AND VIRULENCE IN ACINETOBACTER BAUMANNII.
MICROB DRUG RESIST
NORDMANN P, RODRIGUEZ-VILLODRESA, POIREL L
A SELECTIVE CULTURE MEDIUM FOR SCREENING LINEZOLID-RESISTANT GRAM-POSITIVE BACTE
DIAGN MICROBIOL INFECT DIS
FERNANDEZ-RUIZ M, CARDOZO C, SALAVERT M, AGUILAR-GUISADO M, ESCOLÀ-VERGE L, MUÑOZ P, GIOIA F, MONTEJO M, MERINO P, CUERVO G, GARCIA-VIDAL C, AGUADO JM, CANDIPOP PROJECT, THE CANDI-BUNDLE GROUP, GEIRAS-GEMICOMED (SEIMC)REIPI
CANDIDEMIA IN SOLID ORGAN TRANSPLANT RECIPIENTS IN SPAIN: EPIDEMIOLOGICAL TRENDS AND DETERMINANTS OF OUTCOME.
TRANSPL INFECT DIS
AYERBEALGABA R,ALVAREZ-MARIN R, PRAENAJ,SMANI
ESCHERICHIA COLI CAUSING MENINGITIS IN AN ADULT: A CASE REPORTAND EXPERIMENTAL CHARACTERIZATION OF ITSVIRULENCE.
ENFERM INFECC MICROBIOL CLIN
GARCIA-VIDAL C, ALASTRUEY-IZQUIERDO A, AGUILAR-GUISADO M, CARRATALÀ J, CASTRO C, FERNANDEZ-RUIZ M, AGUADO JM, FERNANDEZ JM, FORTUN J, GARNACHO-MONTERO J, GAVALDÀ J, GUDIOL C, GUINEA J, GOMEZ-LOPEZ A, MUÑOZ P, PEMAN J, ROVIRA M, RUIZ-CAMPSI, CUENCA-ESTRELLA M
EXECUTIVE SUMMARY OF CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF INVASIVE DISEASES CAUSED BY ASPERGILLUS: 2018 UPDATE BY THE GEMICOMED-SEIMC/REIPI.
ENFERM INFECC MICROBIOL CLIN.
LEPEJA, RODRIGUEZ-VILLODRESA, MARTIN-GUTIERREZ G, LUQUE R,AZNAR J
IN VITRO STUDY OF SYNERGY OF AMPICILLIN WITH CEFTRIAXONE AGAINST LISTERIA MONOCYTOGENES.
REVESP QUIMIOTER. 2
HIRZEL C, FERREIRA VH, L'HUILLIER AG, HOSCHLER K, CORDERO E, LIMAYE AP, ENGLUND JA, REID G, HUMAR A, KUMAR D, INFLUENZA IN TRANSPLANT STUDY GROUP
HUMORAL RESPONSE TO NATURAL INFLUENZA INFECTION IN SOLID ORGAN TRANSPLANT RECIPIENTS.
AM J TRANSPLANT.
PEREZ-NADALES E, GUTIERREZ-GUTIERREZ B, NATERA AM, ABDALA E, REINA MAGALHÃES M, MULARONI A, MONACO F, CAMERA PIERROTTI L, PINHEIRO FREIRE M, IYER RN, MEHTA STEINKE S, GRAZIA CALVI E, TUMBARELLO M, FALCONE M, FERNANDEZ-RUIZ M, MARIA COSTA-MATEO J, RANA MM, MARA VAREJÃO STRABELLI T, PAUL M, CARMEN FARIÑAS M, CLEMENTE WT, ROILIDES E, MUÑOZ P, DEWISPELAERE L, LOECHES B, LOWMAN W, HOCK TAN B, ESCUDERO-SANCHEZ R, BODRO M, ANTONIO GROSSI P, SOLDANI F, GUNSEREN F, NESTOROVA N, PASCUAL A, MARTINEZ-MARTINEZ L, AGUADO JM, RODRIGUEZ-BAÑO J, TORRE-CISNEROS J, REIPI/INCREMENT-SOT INVESTIGATORS
PREDICTORS OF MORTALITY IN SOLID ORGAN TRANSPLANT RECIPIENTS WITH BLOODSTREAM INFECTIONS DUE TO CARBAPENEMASE-PRODUCING ENTEROBACTERALES: THE IMPACT OF CYTOMEGALOVIRUS DISEASE AND LYMPHOPENIA.
AM J TRANSPLANT.
MOLINA-ORTEGA A, MARTIN-GANDUL C, MENA-ROMO JD, RODRIGUEZ-HERNANDEZ MJ, SUÑER M, BERNAL C, SANCHEZ M, SANCHEZ-CESPEDES J, PEREZ ROMERO P, CORDERO E
IMPACT OF PRETRANSPLANT CMV-SPECIFIC T-CELL IMMUNE RESPONSE IN THE CONTROL OF CMV INFECTION AFTER SOLID ORGAN TRANSPLANTATION: A PROSPECTIVE COHORT STUDY.
CLIN MICROBIOL INFECT.
RODRIGUEZ-VILLODRES A, BONNIN RA, ORTIZ DE LA ROSA JM, ALVAREZ-MARIN R, NAAS T, AZNAR J, PACHON J, LEPE JA, SMANI Y
PHYLOGENY, RESISTOME, AND VIRULOME OF ESCHERICHIA COLI CAUSING BILIARY TRACT INFECTIONS.
J CLIN MED.
MOLINA J, NOGUER M, LEPE JA, PEREZ-MORENO MA, AGUILAR-GUISADO M, LASSO DE LA VEGA R, PEÑALVA G, CRESPO-RIVAS JC, GIL-NAVARRO MV, SALVADOR J, CISNEROS JM
CLINICAL IMPACT OF AN EDUCATIONAL ANTIMICROBIAL STEWARDSHIP PROGRAM ASSOCIATED WITH INFECTIOUS DISEASES CONSULTATION TARGETING PATIENTS WITH CANCER: RESULTS OF A 9-YEAR QUASI-EXPERIMENTAL STUDY WITH AN INTERRUPTED TIME-SERIES ANALYSIS.
J INFECT.
L'HUILLIER AG, FERREIRA VH, HIRZEL C, CORDERO E, LIMAYE AP, REID G, ENGLUND J, BLUMBERG E, KUMAR D, HUMAR A
CYTOKINE PROFILES AND SEVERITY OF INFLUENZA INFECTION IN TRANSPLANT RECIPIENTS.
J INFECT DIS.
MANGAS EL, RUBIO A, ALVAREZ-MARIN R, LABRADOR-HERRERA G, PACHON J, PACHON-IBAÑEZ ME, DIVINA F, PEREZ-PULIDO AJ
PANGENOME OF ACINETOBACTER BAUMANNII UNCOVERS TWO GROUPS OF GENOMES, ONE OF THEM WITH GENES INVOLVED IN CRISPR/CAS DEFENCE SYSTEMS ASSOCIATED WITH THE ABSENCE OF PLASMIDS AND EXCLUSIVE GENES FOR BIOFILM FORMATION.
MICROB GENOM.
AYERBE-ALGABA R, GIL-MARQUES ML, MIRO-CANTURRI A, PARRA-MILLAN R, PACHON-IBAÑEZ ME, JIMENEZ-MEJIAS ME, PACHON J, SMANI Y
THE ANTHELMINTIC OXYCLOZANIDE RESTORES THE ACTIVITY OF COLISTIN AGAINST COLISTIN-RESISTANT GRAM-NEGATIVE BACILLI.
INT J ANTIMICROB AGENTS.
MIRO-CANTURRI A, AYERBE-ALGABA R, SMANI Y
DRUG REPURPOSING FOR THE TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS.
FRONT MICROBIOL.
JIMENEZ-GONZALEZ V, OGALLA-GARCIA E, GARCIA-QUINTANILLA M, GARCIA-QUINTANILLA A
DECIPHERING GRINA/LIFEGUARD1: NUCLEAR LOCATION, CA2+ HOMEOSTASIS AND VESICLE TRANSPORT.
INT J MOL SCI
BLASCO L, AMBROA A, LOPEZ M, FERNANDEZ-GARCIA L, BLERIOT I, TRASTOY R, RAMOS-VIVAS J, COENYE T, FERNANDEZ-CUENCA F, VILA J, MARTINEZ-MARTINEZ L, RODRIGUEZ-BAÑO J, PASCUAL A, CISNEROS JM, PACHON J, BOU G, TOMAS M
COMBINED USE OF THE AB105-2ΦΔCI LYTIC MUTANT PHAGE AND DIFFERENT ANTIBIOTICS IN CLINICAL ISOLATES OF MULTI-RESISTANT ACINETOBACTER BAUMANNII.
MICROORGANISMS.
MARRUGAL-LORENZO JA, SERNA-GALLEGO A, BERASTEGUI-CABRERA J, PACHON J, SANCHEZ-CESPEDES J
REPOSITIONING SALICYLANILIDE ANTHELMINTIC DRUGS TO TREAT ADENOVIRUS INFECTIONS.
SCI REP
GONZALEZ I, MOLINA-ORTEGA A, PEREZ-ROMERO P, ECHEVARRIA JE, HE L, TARRAGO D
VARICELLA-ZOSTER VIRUS CLADES CIRCULATING IN SPAIN OVER TWO DECADES.
J CLIN VIROL
LOPEZ-CORTES LE, AYERBE-GARCIA R, CARRASCO-HERNANDEZ L, FRAILE-RAMOS E, CARMONA-CABALLERO JM, QUINTANA-GALLEGO E, VALIDO-MORALES A, PRAENA J, PACHON-DIAZ J, DOMUS OPAT GROUP
OUTPATIENT PARENTERAL ANTIMICROBIAL TREATMENT FOR NON-CYSTIC FIBROSIS BRONCHIECTASIS EXACERBATIONS: A PROSPECTIVE MULTICENTRE OBSERVATIONAL COHORT STUDY.
RESPIRATION
MITSUWAN W, JIMENEZ-MUNGUIA I, VISUTTHI M, SIANGLUM W, REIPI/GEIH STUDY GROUP, RODRIGUEZ-ORTEGA MJ, VORAVUTHIKUNCHAI SP
RHODOMYRTONE DECREASES STAPHYLOCOCCUS AUREUS SIGB ACTIVITY DURING EXPONENTIALLY GROWING PHASE AND INHIBITS HAEMOLYTIC ACTIVITY WITHIN MEMBRANE VESICLES.
MICROB PATHOG
ROCA-OPORTO C, CEBRERO-CANGUEIRO T, GIL-MARQUES ML, LABRADOR-HERRERA G, SMANI Y, GONZALEZ-RONCERO FM, MARIN LM, PACHON J, PACHON-IBAÑEZ ME, CORDERO E
PREVALENCE AND CLINICAL IMPACT OF STREPTOCOCCUS PNEUMONIAE NASOPHARYNGEAL CARRIAGE IN SOLID ORGAN TRANSPLANT RECIPIENTS.
BMC INFECT DIS.
XU J, PACHON-IBAÑEZ ME, CEBRERO-CANGUEIRO T, CHEN H, SANCHEZ-CESPEDES J, ZHOU J
DISCOVERY OF NICLOSAMIDE AND ITS O-ALKYLAMINO-TETHERED DERIVATIVES AS POTENT ANTIBACTERIAL AGENTS AGAINST CARBAPENEMASE-PRODUCING AND/OR COLISTIN RESISTANT ENTEROBACTERIACEAE ISOLATES
BIOORG MED CHEM LETT.
ESPINAL P, PANTEL A, ROLO D, MARTI S, LOPEZ-ROJAS R, SMANI Y, PACHON J, VILA J, LAVIGNE JP
RELATIONSHIP BETWEEN DIFFERENT RESISTANCE MECHANISMS AND VIRULENCE IN ACINETOBACTER BAUMANNII.
MICROB DRUG RESIST.
NORDMANN P, RODRIGUEZ-VILLODRES A, POIREL L
A SELECTIVE CULTURE MEDIUM FOR SCREENING LINEZOLID-RESISTANT GRAM-POSITIVE BACTERIA.
DIAGN MICROBIOL INFECT DIS.
FERNANDEZ-RUIZ M, CARDOZO C, SALAVERT M, AGUILAR-GUISADO M, ESCOLÀ-VERGE L, MUÑOZ P, GIOIA F, MONTEJO M, MERINO P, CUERVO G, GARCIA-VIDAL C, AGUADO JM, CANDIPOP PROJECT, THE CANDI-BUNDLE GROUP, GEIRAS-GEMICOMED (SEIMC)REIPI
CANDIDEMIA IN SOLID ORGAN TRANSPLANT RECIPIENTS IN SPAIN: EPIDEMIOLOGICAL TRENDS AND DETERMINANTS OF OUTCOME.
TRANSPL INFECT DIS
AYERBE ALGABA R, ALVAREZ-MARIN R, PRAENA J, SMANI Y
ESCHERICHIA COLI CAUSING MENINGITIS IN AN ADULT: A CASE REPORT AND EXPERIMENTAL CHARACTERIZATION OF ITS VIRULENCE.
ENFERM INFECC MICROBIOL CLIN
GARCIA-VIDAL C, ALASTRUEY-IZQUIERDO A, AGUILAR-GUISADO M, CARRATALÀ J, CASTRO C, FERNANDEZ-RUIZ M, AGUADO JM, FERNANDEZ JM, FORTUN J, GARNACHO-MONTERO J, GAVALDÀ J, GUDIOL C, GUINEA J, GOMEZ-LOPEZ A, MUÑOZ P, PEMAN J, ROVIRA M, RUIZ-CAMPS I, CUENCA-ESTRELLA M
EXECUTIVE SUMMARY OF CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF INVASIVE DISEASES CAUSED BY ASPERGILLUS: 2018 UPDATE BY THE GEMICOMED-SEIMC/REIPI.
ENFERM INFECC MICROBIOL CLIN
LEN O, LOS-ARCOS I, AGUADO JM, BLANES M, BODRO M, CARRATALÀ J, CORDERO E, FARIÑAS MC, FERNANDEZ-RUIZ M, FORTUN J, GAVALDÀ J, LOPEZ-MEDRANO F, LOPEZ-VELEZ R, LUMBRERAS C, MAHILLO B, MARCOS MA, MARTIN-DAVILA P, MONTEJO JM, MORENO A, MUÑOZ P, NORMAN F, PEREZ-SAENZ JL, PUMAROLA T, SABE N, SAN-JUAN R, VIDAL E, DOMINGUEZ-GIL B, TRANSPLANT INFECTION STUDY GROUP (GESITRA) OF THE SPANISH SOCIETY OF INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY (SEIMC), AND THE NATIONAL TRANSPLANT ORGANIZATION (ONT)
EXECUTIVE SUMMARY OF THE CONSENSUS STATEMENT OF THE TRANSPLANT INFECTION STUDY GROUP (GESITRA) OF THE SPANISH SOCIETY OF INFECTIOUS DISEASES AND CLINICAL MICROBIOLOGY (SEIMC) AND THE NATIONAL TRANSPLANT ORGANIZATION (ONT) ON THE SELECTION CRITERIA OF DONORS OF SOLID ORGANS IN RELATION TO INFECTIOUS DISEASES.
ENFERM INFECC MICROBIOL CLIN.
LEPE JA, RODRIGUEZ-VILLODRES A, MARTIN-GUTIERREZ G, LUQUE R, AZNAR J
IN VITRO STUDY OF SYNERGY OF AMPICILLIN WITH CEFTRIAXONE AGAINST LISTERIA MONOCYTOGENES.
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Parra-Millán R, Vila-Farrés X, Ayerbe-Algaba R, Varese M, Sánchez-Encinales V, Bayó N, Pachón-Ibáñez ME, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y.
Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy.
J Antimicrob Chemother
Gil-Marqués ML, Moreno-Martínez P, Costas C, Pachón J, Blázquez J, McConnell MJ.
Peptidoglycan recycling contributes to intrinsic resistance to fosfomycin in Acinetobacter baumannii.
J Antimicrob Chemother
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Effect of hypoxia on the pathogenesis of Acinetobacter baumannii and Pseudomonas aeruginosa in vitro and in murine experimental models of infections.
Infect Immun.
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Ghashghaei O, Caputo S, Sintes M, Revés M, Kielland N, Estarellas C, Luque FJ, Aviñó A, Eritja R, Serna-Gallego A, Marrugal-Lorenzo JA, Pachón J, Sánchez-Céspedes J, Treadwell R, de Moliner F, Vendrell M, Lavilla R.
Multiple Multicomponent Reactions: Unexplored Substrates, Selective Processes, and Versatile Chemotypes in Biomedicine.
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Pulido MR, García-Quintanilla M, Pachón J, McConnell MJ.
Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection.
Vaccine
Pachón-Ibáñez ME, Labrador-Herrera G, Cebrero-Cangueiro T, Díaz C, Smani Y, Del Palacio JP, Rodríguez-Baño J, Pascual A, Pachón J, Conejo MC.
Efficacy of Colistin and Its Combination With Rifampin in Vitro and in Experimental Models of Infection Caused by Carbapenemase-Producing Clinical Isolates of Klebsiella pneumoniae.
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Parra-Millán R, Guerrero-Gómez D, Ayerbe-Algaba R, Pachón-Ibáñez ME, Miranda-Vizuete A, Pachón J, Smani Y.
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB.
mSphere
Aguado JM, Silva JT, Fernández-Ruiz M, Cordero E, Fortún J, Gudiol C, Martínez-Martínez L, Vidal E, Almenar L, Almirante B, Cantón R, Carratalá J, Castón JJ, Cercenado E, Cervera C, Cisneros JM, Crespo-Leiro MG, Cuervas-Mons V, Elizalde-Fernández J, Fariñas MC, Gavaldà J, Goyanes MJ, Gutiérrez-Gutiérrez B, Hernández D, Len O, López-Andújar R, López-Medrano F, Martín-Dávila P, Montejo M, Moreno A, Oliver A, Pascual A, Pérez-Nadales E, Román-Broto A, San-Juan R, Serón D, Solé-Jover A, Valerio M, Muñoz P, Torre-Cisneros J, Spanish Society of Transplantation (SET), Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases and Clinical Microbiology (GESITRA-SEIMC), Spanish Network for Research in Infectious Diseases (REIPI) (RD16/0016).
Management of multidrug resistant Gram-negative bacilli infections in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations.
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Ayerbe-Algaba R, Gil-Marqués ML, Jiménez-Mejías ME, Sánchez-Encinales V, Parra-Millán R, Pachón-Ibáñez ME, Pachón J, Smani Y.
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Cebrero-Cangueiro T, Álvarez-Marín R, Labrador-Herrera G, Smani Y, Cordero-Matía E, Pachón J, Pachón-Ibáñez ME
In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae.
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Fernández-García L, Ambroa A, Blasco L, Bleriot I, López M, Álvarez-Marín R, Fernández-Cuenca F, Martínez-Martínez L, Vila J, Rodríguez-Baño J, Garnacho-Montero J, Cisneros JM, Pascual A, Pachón J, Bou G, Smani Y, Tomás M
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García-Vidal C, Alastruey-Izquierdo A, Aguilar-Guisado M, Carratalà J, Castro C, Fernández-Ruiz M, Aguado JM, Fernández JM, Fortún J, Garnacho-Montero J, Gavaldà J, Gudiol C, Guinea J, Gómez-López A, Muñoz P, Pemán J, Rovira M, Ruiz-Camps I, Cuenca-Estrella M
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Gil-Marqués ML, Moreno-Martínez P, Costas C, Pachón J, Blázquez J, McConnell MJ.
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J Antimicrob Chemother.
Gil-Marqués ML, Pachón-Ibáñez ME, Pachón J, Smani Y.
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Gudiol C, Nicolae S, Royo-Cebrecos C, Aguilar-Guisado M, Montero I, Martín-Gandul C, Perayre M, Berbel D, Encuentra M, Arnan M, Cisneros-Herreros JM, Carratalà J.
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Kumar D, Ferreira VH, Blumberg E, Silveira F, Cordero E, Pérez-Romero P, Aydillo T, Danziger-Isakov L, Limaye AP, Carratala J, Muñoz P, Montejo M, López-Medrano F, Farinas MC, Gavalda J, Moreno A, Levi M, Fortun J, Torre-Cisneros J, Englund JA, Natori Y, Husain S, Reid G, Sharma TS, Humar A.
A 5-Year Prospective Multicenter Evaluation of Influenza Infection in Transplant Recipients.
Clin Infect Dis.
López-Medrano F, Fernández-Ruiz M, Silva JT, Carver PL, van Delden C, Merino E, Pérez-Sáez MJ, Montero M, Coussement J, de Abreu Mazzolin M, Cervera C, Santos L, Sabé N, Scemla A, Cordero E, Cruzado-Vega L, Martín-Moreno PL, Len Ó, Rudas E, Ponce de León A, Arriola M, Lauzurica R, David MD, González-Rico C, Henríquez-Palop F, Fortún J, Nucci M, Manuel O, Paño-Pardo JR, Montejo M, Vena A, Sánchez-Sobrino B, Mazuecos A, Pascual J, Horcajada JP, Lecompte T, Moreno A, Carratalà J, Blanes M, Hernández D, Hernández-Méndez EA, Fariñas MC, Perelló-Carrascosa M, Muñoz P, Andrés A, Aguado JM, Spanish Network for Research in Infectious Diseases (REIPI), Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC), Study Group for Infections in Compromised Hosts (ESGICH) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Swiss Transplant Cohort Study (STCS).
Multinational case-control study of risk factors for the development of late invasive pulmonary aspergillosis following kidney transplantation.
. Clin Microbiol Infect.
Pulido MR, García-Quintanilla M, Pachón J, McConnell MJ.
Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection.
Vaccine
Marrugal-Lorenzo JA, Serna-Gallego A, González-González L, Buñuales M, Poutou J, Pachón J, González-Aparicio M, Hernández-Alcoceba R, Sánchez-Céspedes J
Inhibition of adenovirus infection by mifepristone.
Antiviral Res
Martín-Gandul C, Pérez-Romero P, Mena-Romo D, Molina-Ortega A, González-Roncero FM, Suñer M, Bernal G, Cordero E, Spanish Network for Research in Infectious Diseases (REIPI)
Kinetic of the CMV-specific T-cell immune response and CMV infection in CMV-seropositive kidney transplant recipients receiving rabbit anti-thymocyte globulin induction therapy: A pilot study
Transpl Infect Dis
Molina-Ortega A, Martín-Gandul C, Mena-Romo JD, Rodríguez-Hernández MJ, Suñer M, Bernal C, Sánchez M, Sánchez-Céspedes J, Pérez Romero P, Cordero E
Impact of pretransplant CMV-specific T-cell immune response in the control of CMV infection after solid organ transplantation: a prospective cohort study.
Clin Microbiol Infect.
Pachón-Ibáñez ME, Labrador-Herrera G, Cebrero-Cangueiro T, Díaz C, Smani Y, Del Palacio JP, Rodríguez-Baño J, Pascual A, Pachón J, Conejo MC
Efficacy of Colistin and Its Combination With Rifampin in Vitro and in Experimental Models of Infection Caused by Carbapenemase-Producing Clinical Isolates of Klebsiella pneumoniae.
Front Microbiol.
Páez-Vega A, Poyato A, Rodríguez-Benot A, Guirado L, Fortún J, Len O, Abdala E, Fariñas MC, Cordero E, de Gracia C, Hernández D, González R, Torre-Cisneros J, Cantisán S, Spanish Network for Research in Infectious Diseases (REIPI) (RD16/0016), Spanish Renal Disease Network (REDinREN, RD16/0009).
Analysis of spontaneous resolution of cytomegalovirus replication after transplantation in CMV-seropositive patients with pretransplant CD8+IFNG+ response.
Antiviral Res.
. Parra-Millán R, Guerrero-Gómez D, Ayerbe-Algaba R, Pachón-Ibáñez ME, Miranda-Vizuete A, Pachón J, Smani Y
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB
mSphere.
Parra-Millán R, Vila-Farrés X, Ayerbe-Algaba R, Varese M, Sánchez-Encinales V, Bayó N, Pachón-Ibáñez ME, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y.
Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy.
J AntimiCrob Chemother.
Aguado JM, Silva JT, Fernández-Ruiz M, Cordero E, Fortún J, Gudiol C, Martínez-Martínez L, Vidal E, Almenar L, Almirante B, Cantón R, Carratalá J, Castón JJ, Cercenado E, Cervera C, Cisneros JM, Crespo-Leiro MG, Cuervas-Mons V, Elizalde-Fernández J, Fariñas MC, Gavaldà J, Goyanes MJ, Gutiérrez-Gutiérrez B, Hernández D, Len O, López-Andújar R, López-Medrano F, Martín-Dávila P, Montejo M, Moreno A, Oliver A, Pascual A, Pérez-Nadales E, Román-Broto A, San-Juan R, Serón D, Solé-Jover A, Valerio M, Muñoz P, Torre-Cisneros J, Spanish Society of Transplantation (SET), Group for Study of Infection in Transplantation of the Spanish Society of Infectious Diseases and Clinical Microbiology (GESITRA-SEIMC), Spanish Network for Research in Infectious Diseases (REIPI) (RD16/0016).
Management of multidrug resistant Gram-negative bacilli infections in solid organ transplant recipients: SET/GESITRA-SEIMC/REIPI recommendations.
Transplant Rev (Orlando).
Ayerbe Algaba R, Álvarez-Marín R, Praena J, Smani Y.
Escherichia coli causing meningitis in an adult: A case report and experimental characterization of its virulence.
Enferm Infecc Microbiol Clin.
Ayerbe-Algaba R, Gil-Marqués ML, Jiménez-Mejías ME, Sánchez-Encinales V, Parra-Millán R, Pachón-Ibáñez ME, Pachón J, Smani Y.
Synergistic Activity of Niclosamide in Combination With Colistin Against Colistin-Susceptible and Colistin-Resistant Acinetobacter baumannii and Klebsiella pneumoniae.
Front Cell Infect Microbiol.
Carretero-Ledesma M, García-Quintanilla M, Martín-Peña R, Pulido MR, Pachón J, McConnell MJ.
Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii.
Virulence.
Cebrero-Cangueiro T, Álvarez-Marín R, Labrador-Herrera G, Smani Y, Cordero-Matía E, Pachón J, Pachón-Ibáñez ME.
In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae.
Front Cell Infect Microbiol.
Fernández-García L, Ambroa A, Blasco L, Bleriot I, López M, Álvarez-Marín R, Fernández-Cuenca F, Martínez-Martínez L, Vila J, Rodríguez-Baño J, Garnacho-Montero J, Cisneros JM, Pascual A, Pachón J, Bou G, Smani Y, Tomás M.
Relationship Between the Quorum Network (Sensing/Quenching) and Clinical Features of Pneumonia and Bacteraemia Caused by A. baumannii.
Front Microbiol.
García-Vidal C, Alastruey-Izquierdo A, Aguilar-Guisado M, Carratalà J, Castro C, Fernández-Ruiz M, Aguado JM, Fernández JM, Fortún J, Garnacho-Montero J, Gavaldà J, Gudiol C, Guinea J, Gómez-López A, Muñoz P, Pemán J, Rovira M, Ruiz-Camps I, Cuenca-Estrella M.
Executive summary of clinical practice guideline for the management of invasive diseases caused by Aspergillus: 2018 Update by the GEMICOMED-SEIMC/REIPI.
Enferm Infecc Microbiol Clin.
Gil-Marqués ML, Moreno-Martínez P, Costas C, Pachón J, Blázquez J, McConnell MJ.
Peptidoglycan recycling contributes to intrinsic resistance to fosfomycin in Acinetobacter baumannii.
J Antimicrob Chemother.
Gil-Marqués ML, Pachón-Ibáñez ME, Pachón J, Smani Y.
Effect of Hypoxia on the Pathogenesis of Acinetobacter baumannii and Pseudomonas aeruginosa In Vitro and in Murine Experimental Models of Infection.
Infect Immun. 2018
). Gudiol C, Nicolae S, Royo-Cebrecos C, Aguilar-Guisado M, Montero I, Martín-Gandul C, Perayre M, Berbel D, Encuentra M, Arnan M, Cisneros-Herreros JM, Carratalà J.
Administration of taurolidine-citrate lock solution for prevention of central venous catheter infection in adult neutropenic haematological patients: a randomised, double-blinded, placebo-controlled trial (TAURCAT).
Trials.
Kumar D, Ferreira VH, Blumberg E, Silveira F, Cordero E, Pérez-Romero P, Aydillo T, Danziger-Isakov L, Limaye AP, Carratala J, Muñoz P, Montejo M, López-Medrano F, Farinas MC, Gavalda J, Moreno A, Levi M, Fortun J, Torre-Cisneros J, Englund JA, Natori Y, Husain S, Reid G, Sharma TS, Humar A.
A 5-Year Prospective Multicenter Evaluation of Influenza Infection in Transplant Recipients.
Clin Infect Dis.
López-Medrano F, Fernández-Ruiz M, Silva JT, Carver PL, van Delden C, Merino E, Pérez-Sáez MJ, Montero M, Coussement J, de Abreu Mazzolin M, Cervera C, Santos L, Sabé N, Scemla A, Cordero E, Cruzado-Vega L, Martín-Moreno PL, Len Ó, Rudas E, Ponce de León A, Arriola M, Lauzurica R, David MD, González-Rico C, Henríquez-Palop F, Fortún J, Nucci M, Manuel O, Paño-Pardo JR, Montejo M, Vena A, Sánchez-Sobrino B, Mazuecos A, Pascual J, Horcajada JP, Lecompte T, Moreno A, Carratalà J, Blanes M, Hernández D, Hernández-Méndez EA, Fariñas MC, Perelló-Carrascosa M, Muñoz P, Andrés A, Aguado JM, Spanish Network for Research in Infectious Diseases (REIPI), Group for the Study of Infection in Transplant Recipients (GESITRA) of the Spanish Society of Clinical Microbiology and Infectious Diseases (SEIMC), Study Group for Infections in Compromised Hosts (ESGICH) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Swiss Transplant Cohort Study (STCS).
Multinational case-control study of risk factors for the development of late invasive pulmonary aspergillosis following kidney transplantation.
Clin Microbiol Infect.
Marrugal-Lorenzo JA, Serna-Gallego A, González-González L, Buñuales M, Poutou J, Pachón J, González-Aparicio M, Hernández-Alcoceba R, Sánchez-Céspedes J.
Inhibition of adenovirus infection by mifepristone.
Antiviral Res.
Martín-Gandul C, Pérez-Romero P, Mena-Romo D, Molina-Ortega A, González-Roncero FM, Suñer M, Bernal G, Cordero E, Spanish Network for Research in Infectious Diseases (REIPI).
Kinetic of the CMV-specific T-cell immune response and CMV infection in CMV-seropositive kidney transplant recipients receiving rabbit anti-thymocyte globulin induction therapy: A pilot study.
Transpl Infect Dis.
Molina-Ortega A, Martín-Gandul C, Mena-Romo JD, Rodríguez-Hernández MJ, Suñer M, Bernal C, Sánchez M, Sánchez-Céspedes J, Pérez Romero P, Cordero E.
Impact of pretransplant CMV-specific T-cell immune response in the control of CMV infection after solid organ transplantation: a prospective cohort study
Clin Microbiol Infect.
Pachón-Ibáñez ME, Labrador-Herrera G, Cebrero-Cangueiro T, Díaz C, Smani Y, Del Palacio JP, Rodríguez-Baño J, Pascual A, Pachón J, Conejo MC.
Efficacy of Colistin and Its Combination With Rifampin in Vitro and in Experimental Models of Infection Caused by Carbapenemase-Producing Clinical Isolates of Klebsiella pneumoniae.
Front Microbiol.
. Páez-Vega A, Poyato A, Rodríguez-Benot A, Guirado L, Fortún J, Len O, Abdala E, Fariñas MC, Cordero E, de Gracia C, Hernández D, González R, Torre-Cisneros J, Cantisán S, Spanish Network for Research in Infectious Diseases (REIPI) (RD16/0016), Spanish Renal Disease Network (REDinREN, RD16/0009).
Analysis of spontaneous resolution of cytomegalovirus replication after transplantation in CMV-seropositive patients with pretransplant CD8+IFNG+ response.
Antiviral Res.
Parra-Millán R, Guerrero-Gómez D, Ayerbe-Algaba R, Pachón-Ibáñez ME, Miranda-Vizuete A, Pachón J, Smani Y.
Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB.
mSphere.
Parra-Millán R, Vila-Farrés X, Ayerbe-Algaba R, Varese M, Sánchez-Encinales V, Bayó N, Pachón-Ibáñez ME, Teixidó M, Vila J, Pachón J, Giralt E, Smani Y.
Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy.
J Antimicrob Chemother.
Pulido MR, García-Quintanilla M, Pachón J, McConnell MJ.
Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection.
Vaccine
Mena-Romo JD, Pérez Romero P, Martín-Gandul C, Gentil MÁ, Suárez-Artacho G, Lage E, Sánchez M, Cordero E.
CMV-specific T-cell immunity in solid organ transplant recipients at low risk of CMV infection. Chronology and applicability in preemptive therapy.
J Infect.
CISNEROS JM, ROSSO-FERNANDEZ CM, ROCA-OPORTO C, DE PASCALE G, JIMENEZ-JORGE S, FERNANDEZ-HINOJOSA E, MATTHAIOU DK, RAMIREZ P, DIAZ-MIGUEL RO, ESTELLA A, ANTONELLI M, DIMOPOULOS G, GARNACHO-MONTERO J, MAGIC BULLET WORKING GROUP WP1
COLISTIN VERSUS MEROPENEM IN THE EMPIRICAL TREATMENT OF VENTILATOR-ASSOCIATED PNEUMONIA (MAGIC BULLET STUDY): AN INVESTIGATOR-DRIVEN, OPEN-LABEL, RANDOMIZED, NONINFERIORITY CONTROLLED TRIAL.
CRIT CARE