Infectious Diseases and the Immune System

HIV infection and the pharmacokinetics of antiviral drugs

Luis Fernando López Cortés
Luis Fernando López Cortés
IBiS
Campus Hospital Universitario Virgen del Rocío
Avda. Manuel Siurot, s/n.
41013 · Sevilla

Laboratory: 213
Ezequiel Ruiz-Mateos Carmona
Ezequiel Ruiz-Mateos Carmona
IBiS
Campus Hospital Universitario Virgen del Rocío
Avda. Manuel Siurot, s/n.
41013 · Sevilla
Laboratory: 211

Luis Fernando López Cortés

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  1. Group members
  2. Research areas
  3. Publications

Group: HIV infection and the pharmacokinetics of antiviral drugs

Directory
Group members HIV infection and the pharmacokinetics of antiviral drugs
  • Domínguez Molina, Beatriz.Lda. en Farmacia
  • Espinosa Aguilera, Nuria.FEA HUVR
  • Fernández Magdaleno, Tamara.FP2. Técnico/a de Laboratorio.
  • Gasca Capote, Mª del Carmen.Investigadora Predoctoral
  • Gutiérrez Valencia, Alicia.PhD in Pharmacy. Post-doctoral fellow.
  • Herrera Hidalgo, Laura.Lda. en Farmacia. Técnico.
  • Jiménez León, Mª Reyes.Investigadora Predoctoral
  • Llaves Flores, Silvia.Lda. Documentación
  • López Cortés, Luis Fernando.MD/PhD. Faculty Staff - Internal Medicine/Assistant Professor (HUVR/US).
  • Milanés Guisado, Yusnelkis.Dra. Documentación
  • Muñoz Muela, Esperanza.Investigadora Predoctoral
  • Neukam, Karin.Investigadora Miguel Servet I
  • Pablo Bernal, Rebeca de.Degree in Veterinary. PhD student.
  • Rafii-el-Idrissi Benhnia, Mohammed.PhD in Biology. Senior Research Ramón y Cajal.
  • Rivas Jeremías, Inmaculada.Degree in Pharmacy. Technician.
  • Rubio Ponce, Sofía.Investigadora Postdoctoral
  • Ruiz-Mateos Carmona, Ezequiel.PhD in Biochemistry. Post-doctoral fellow Miguel Servet.
  • Tarancón Díez, Laura.Lda. en Biología
  • Trujillo Rodríguez , María.Lda. Bioquímica. Predoctoral.
  • Viciana Fernández, Pompeyo Eduardo.MD/PhD. Section Head -Internal Medicine (HUVR).

Research areas

Pharmacokinetics of antiviral drugs.

In this line of research pharmacokinetic, pharmacodynamic and interaction studies are carried out, both in plasma and at the intracellular level, in humans and experimental models, on antiviral drugs related to infection by HIV, hepatitis C virus and cytomegalovirus. Particular attention is given to those studies with immediate clinical application such as the reduction of dosages of some drugs against HIV or HCV, guided by their plasma concentrations or the analysis of different dosage guidelines to avoid their adverse effects. Also, therapeutic monitoring programs of anti-retrovirals are carried out in special situations such as gestation or liver cirrhosis. Several of these projects have been carried out in collaboration with other hospitals of the Andalusian Health Service (SAS), within the context of the Andalusian Society of Infectious Diseases (SAEI). In the last few years, several of these studies have been carried out, and others are under way, such as clinical trials promoted by our own researchers, with no relationship to the pharmaceutical industry.