Begley, V; Jordan-Pla, A; Penate, X; Garrido-Godino, AI; Challal, D; Cuevas-Bermudez, A; Mitjavila, A; Barucco, M; Gutierrez, G; Singh, A; Alepuz, P; Navarro, F; Libri, D; Perez-Ortin, JE; Chavez, S
Xrn1 influence on gene transcription results from the combination of general effects on elongating RNA pol II and gene-specific chromatin configuration
RNA BIOLOGY
Olmedo-Pelayo, J; Rubio-Contreras, D; Gomez-Herreros, F
Canonical non-homologous end-joining promotes genome mutagenesis and translocations induced by transcription-associated DNA topoisomerase 2 activity
NUCLEIC ACIDS RESEARCH
Penate, X; Praena-Fernandez, JM; Pareja, PR; Enguix-Riego, MD; Payan-Bravo, L; Vieites, B; Gomez-Izquierdo, L; Olasolo, JJ; del Campo, ER; Reyes, JC; Chavez, S; Lopez Guerra, JL
Overexpression of Canonical Prefoldin Associates with the Risk of Mortality and Metastasis in Non-Small Cell Lung Cancer
CANCERS
Begley V, Corzo D, Jordán-Pla A, Cuevas-Bermúdez A, Miguel-Jiménez L, Pérez-Aguado D, Machuca-Ostos M, Navarro F, Chávez MJ, Pérez-Ortín JE, Chávez S
The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4.
Nucleic Acids Res.
Pérez-Ortín JE, Tordera V, Chávez S
Homeostasis in the Central Dogma of molecular biology: the importance of mRNA instability.
RNA Biol.
Ramos-Sáenz A, González-Álvarez D, Rodríguez-Galán O, Rodríguez-Gil A, Gaspar SG, Villalobo E, Dosil M, de la Cruz J
Pol5 is an essential ribosome biogenesis factor required for 60S ribosomal subunit maturation in Saccharomyces cerevisiae.
RNA.
Gómez-Herreros F
DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II.
Front Mol Biosci.
Martinez-Macias MI, Moore DA, Green RL, Gomez-Herreros F, Naumann M, Hermann A, Van Damme P, Hafezparast M, Caldecott KW
FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress.
Life Sci Alliance
Maya Miles D, Peñate X, Sanmartín Olmo T, Jourquin F, Muñoz Centeno MC, Mendoza M, Simon MN, Chavez S, Geli V
High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1.
eLife 7. pii: e35337. doi: 10.7554/eLife.35337.
de la Cruz J, Gómez-Herreros F, Rodríguez-Galán O, Begley V, de la Cruz Muñoz-Centeno M, Chávez S
Feedback regulation of ribosome assembly.
Current Genetics. 64:393-404. doi: 10.1007/s00294-017-0764-x.
Martínez-Fernández V, Garrido-Godino AI, Mirón-García MC, Begley V, Fernández-Pévida A, de la Cruz J, Chávez S, Navarro F
Rpb5 modulates the RNA polymerase II transition from initiation to elongation by influencing Spt5 association and backtracking.
Biochim Biophys Acta 1861:1-13. doi: 10.1016/j.bbagrm.2017.11.002.
de la Cruz J, Gómez-Herreros F, Rodríguez-Galán O, Begley V, de la Cruz Muñoz-Centeno M, Chávez S.
Feedback regulation of ribosome assembly.
Curr Genet
Martínez-Fernández V, Garrido-Godino AI, Mirón-García MC, Begley V, Fernández-Pévida A, de la Cruz J, Chávez S, Navarro F.
Rpb5 modulates the RNA polymerase II transition from initiation to elongation by influencing Spt5 association and backtracking.
Biochim Biophys Acta Gene Regul Mech
Maya Miles D, Peñate X, Sanmartín Olmo T, Jourquin F, Muñoz Centeno MC, Mendoza M, Simón MN, Chávez S, Geli V.
High levels of histones promote whole-genome-duplications and trigger a Swe1WEE1-dependent phosphorylation of Cdc28CDK1
Elife
