Enfermedades infecciosas y del sistema inmunitario

Enfermedades infecciosas

María Elisa Cordero Matía
María Elisa Cordero Matía
IBiS
Campus Hospital Universitario Virgen del Rocío
Avda. Manuel Siurot, s/n.
41013 · Sevilla
Laboratorio: 208
Jerónimo Pachón Díaz
Jerónimo Pachón Díaz
IBiS
Campus Hospital Universitario Virgen del Rocío
Avda. Manuel Siurot, s/n.
41013 · Sevilla
Laboratorio: 208

Jerónimo Pachón Díaz

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  1. Miembros del grupo
  2. Áreas de trabajo
  3. Publicaciones

Grupo: Enfermedades infecciosas

Directorio
Miembros del grupo Enfermedades infecciosas
  • Aguilar Guisado, Manuela.Doctora en Medicina y Cirugía. FEA (HUVR).
  • Balsera Manzanero, María.Investigadora Predoctoral
  • Berastegui Cabrera, Judith.Lda. en Biología. Técnico.
  • Carretero Ledesma, Marta.Licenciada en Biología. Doctora en Biomedicina
  • Cerrada Romero, Cristina.Investigadora en Formación. Lda. en Biología
  • Cordero Matía, María Elisa.Doctora en Medicina y Cirugía. FEA (HUVR).
  • Gálvez Benítez, Lydia.Lda. en Medicina y Cirugía
  • Herrera Espejo, Soraya.Lda. en Biología. Técnico.
  • Pachón Díaz, Jerónimo.Doctor en Medicina y Cirugía. Catedrático (Univ. de Sevilla).
  • Roca Oporto, Cristina.Lda. en Medicina y Cirugía. MIR-Medicina Interna (HUVR).
  • Rodríguez Hernández, Mª Jesús.Doctora en Medicina y Cirugía. FEA.
  • Salto Alejandre, Sonsoles.MIR HUVR
  • Sánchez Céspedes, Javier.Doctor en Biología. Investigador Estabilizado del Programa Nicolás Monardes del Sistema Andaluz de Salud
  • Smani, Younes.Doctor en Biología. Investigador Miguel Servet.
  • Vila Domínguez, Andrea.Investigadora Predoctoral PFIS

Áreas de trabajo

ÁREAS DE TRABAJO

La labor científica realizada por nuestro grupo se centra en diversas líneas:

Alternativas terapéuticas en infecciones por bacterias multirresistentes.

A través de esta línea se realizan proyectos de evaluación de nuevos tratamientos antimicrobianos para infecciones por bacterias con diferentes mecanismos de resistencia, tales como Acinetobacter baumannii, Staphylococcus aureus, Escherichia coli y Klebsiella pneumoniae, mediante el estudio en diversos modelos experimentales animales de infecciones, tales como neumonía, meningitis, sepsis peritoneal, cuerpo extraño y endocarditis, en los cuales se llevan a cabo estudios in vitro, análisis farmacocinéticos/farmacodinámicos y eficacia terapéutica in vivo, evaluada por diferentes parámetros.

Dentro de esta línea de realizan estudios con antimicrobianos de uso habitual en clínica humana, para evaluar su actividad sobre bacterias con mecanismos de resistencia prevalentes o su uso en nuevas combinaciones, así como también se realizan estudios para la evaluación de nuevas moléculas con actividad antimicrobiana, en fase de desarrollo preclínica. Diferentes proyectos en esta línea son llevados a cabo como estudios coordinados con otros grupos de investigación españoles, mayormente de la Red Española de Investigación en Patología Infecciosa (Instituto de Salud Carlos III).

 

Infecciones en pacientes inmunodeprimidos.

Se realizan estudios de infecciones en receptores de trasplantes de órgano sólido y de progenitores hematopoyéticos y en pacientes con cáncer, con métodos de epidemiología clínica, sobre la incidencia y factores de riesgo, etiología, características clínicas, y pronósticas de las infecciones en estos grupos de pacientes, así como sobre el síndrome de neutropenia febril post-quimioterapia.

Las infecciones en estudio son las bacteriemias, las neumonías, la infección de la herida quirúrgica y la infección urinaria. Igualmente infecciones por microorganismos específicos como citomegalovirus, Aspergillus spp. y Klebsiella pneumoniae productora de BLEE. En esta línea se realizan estudios sobre aspectos concretos de las infecciones fúngicas como el tratamiento antifúngico empírico en pacientes seleccionados con neutropenia y fiebre persistente.

 

Infecciones en trasplantes y pacientes oncohematologicos.

Las infecciones víricas como las causadas por virus respiratorias son una de las principales causas de morbilidad y mortalidad en pacientes inmunodeprimidos como son los receptores de trasplante. A través de esta línea se está realizando un estudio de la relación entre la inmunidad específica frente a virus y la evolución de la infección/enfermedad causada por el mismo. En los estudios de la enfermedad causada por virus tras el trasplante, optimizamos técnicas moleculares de detección de herpes virus, virus parainfluenza, adenovirus y virus respiratorio sincitial, así como otros virus emergentes, o de reciente diagnóstico, de los que aún no es bien conocida su epidemiología y pronóstico.

 

Revistas Internacionales
Los-Arcos, I; Iacoboni, G; Aguilar-Guisado, M; Alsina-Manrique, L; de Heredia, CD; Fortuny-Guasch, C; Garcia-Cadenas, I; Garcia-Vidal, C; Gonzalez-Vicent, M; Hernani, R; Kwon, M; Machado, M; Martinez-Gomez, X; Maldonado, VO; Pla, CP; Pinana, JL; Pomar, V; Reguera-Ortega, JL; Salavert, M; Soler-Palacin, P; Vazquez-Lopez, L; Barba, P; Ruiz-Camps, I
Recommendations for screening, monitoring, prevention, and prophylaxis of infections in adult and pediatric patients receiving CAR T-cell therapy: a position paper
INFECTION
Mazzotta, S; Cebrero-Cangueiro, T; Frattaruolo, L; Vega-Holm, M; Carretero-Ledesma, M; Sanchez-Cespedes, J; Cappello, AR; Aiello, F; Pachon, J; Vega-Perez, JM; Iglesias-Guerra, F; Pachon-Ibanez, ME
Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Aranzana-Climent, V; Buyck, JM; Smani, Y; Pachon-Diaz, J; Marchand, S; Couet, W; Gregoire, N
Semi-mechanistic PK/PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii
CLINICAL MICROBIOLOGY AND INFECTION
Berenguer, J; Ryan, P; Rodriguez-Bano, J; Jarrin, I; Carratala, J; Pachon, J; Yllescas, M; Arriba, JR
Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain
CLINICAL MICROBIOLOGY AND INFECTION
Rodriguez-Villodres, A; Lepe, JA; Blazquez, J; Aznar, J
Effect of subinhibitory concentrations of ampicillin on Listeria monocytogenes
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Cordero, E; Goycochea-Valdivia, W; Mendez-Echevarria, A; Allende, LM; Alsina, L; Garcia-Morato, MB; Gil-Herrera, J; Gudiol, C; Len-Abad, O; Lopez-Medrano, F; Moreno-Perez, D; Munoz, P; Olbrich, P; Sanchez-Ramon, S; Soler-Palacin, P; Cros, CA; Arostegui, JI; Serra, IB; Carbone, J; Fortun, J; Gonzalez-Granado, LI; Lopez-Granados, E; Lucena, JM; Parody, R; Ramakers, J; Regueiro, JR; Riviere, JG; Roca-Oporto, C; Pena, RR; Santos-Perez, JL; Rodriguez-Gallego, C; Neth, O
Executive Summary of the Consensus Document on the Diagnosis and Management of Patients with Primary Immunodeficiencies
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Gudiol, C; Aguilar-Guisado, M; Azanza, JR; Candel, FJ; Canton, R; Carratala, J; Garcia-Vidal, C; Jarque, I; Lizasoain, M; Gil-Bermejo, JM; Ruiz-Camps, I; Sanchez-Ortega, I; Solano, C; Suarez-Lledo, M; Vazquez, L; de la Camara, R
Executive summary of the consensus document of the Spanish Society of Infectious Diseases and Clinical Microbiolog
ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Mazzotta, S; Marrugal-Lorenzo, JA; Vega-Holm, M; Serna-Gallego, A; Alvarez-Vidal, J; Berastegui-Cabrera, J; del Palacio, JP; Diaz, C; Aiello, F; Pachon, J; Iglesias-Guerra, F; Vega-Perez, JM; Sanchez-Cespedes, J
Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Aguilar-Guisado, M; Marrugal-Lorenzo, JA; Berastegui-Cabrera, J; Merino, L; Pachon, J; Sanchez-Cespedes, J
In vitro co-infection by cytomegalovirus improves the antiviral activity of ganciclovir against human adenovirus
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Cordero, E; Goycochea-Valdivia, W; Mendez-Echevarria, A; Allende, LM; Alsina, L; Garcia-Morato, MB; Gil-Herrera, J; Gudiol, C; Len-Abad, O; Lopez-Medrano, F; Moreno-Perez, D; Munoz, P; Olbrich, P; Sanchez-Ramon, S; Soler-Palacin, P; Cros, CA; Arostegui, JI; Serra, IB; Carbone, J; Fortun, J; Gonzalez-Granado, LI; Lopez-Granados, E; Lucena, JM; Parody, R; Ramakers, J; Regueiro, JR; Riviere, JG; Roca-Oporto, C; Pena, RR; Santos-Perez, JL; Rodriguez-Gallego, C; Neth, O
Executive Summary of the Consensus Document on the Diagnosis and Management of Patients with Primary Immunodeficiencies
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
Alvarez-Marin, R; Navarro-Amuedo, D; Gasch-Blasi, O; Rodriguez-Martinez, JM; Calvo-Montes, J; Lara-Contreras, R; Lepe-Jimenez, JA; Tubau-Quintano, F; Cano-Garcia, ME; Rodriguez-Lopez, F; Rodriguez-Bano, J; Pujol-Rojo, M; Torre-Cisneros, J; Martinez-Martinez, L; Pascual-Hernandez, A; Jimenez-Mejias, ME; Alvarez-Martinez, R; Calvo, J; de Cueto, M; Cano, ME; de Teran, TD; Dominguez-Herrera, J; Mazarrasa, CF; Gasch, O; Martin-Gandul, C; Diaz, JP; Pujol, M; Puppo, I; Smani, Y; Tubau, F; de la Torre-Cisneros, J
A prospective, multicenter case control study of risk factors for acquisition and mortality in Enterobacter species bacteremia
JOURNAL OF INFECTION
Pulido, MR; Garcia-Quintanilla, M; Pachon, J; McConnell, MJ
A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection
VACCINE
Xu, JM; Berastegui-Cabrera, J; Ye, N; Carretero-Ledesma, M; Pachon-Diaz, J; Chen, HY; Pachon-Ibanez, ME; Sanchez-Cespedes, J; Zhou, J
Discovery of Novel Substituted N-(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
Xu, JM; Berastegui-Cabrera, J; Chen, HY; Pachon, J; Zhou, J; Sanchez-Cespedes, J
Structure-Activity Relationship Studies on Diversified Salicylamide Derivatives as Potent Inhibitors of Human Adenovirus Infection
JOURNAL OF MEDICINAL CHEMISTRY
Labrador-Herrera, G; Perez-Pulido, AJ; Alvarez-Marin, R; Casimiro-Soriguer, CS; Cebrero-Cangueiro, T; Moran-Barrio, J; Pachon, J; Viale, AM; Pachon-Ibanez, ME
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii
VIRULENCE
Miro-Canturri, A; Ayerbe-Algaba, R; Villodres, AR; Pachon, J; Smani, Y
Repositioning rafoxanide to treat Gram-negative bacilli infections
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Gil-Marques, ML; Herrera, GL; Canturri, AM; Pachon, J; Smani, Y; Pachon-Ibanez, ME
Role of PstS in the Pathogenesis of Acinetobacter baumannii Under Microaerobiosis and Normoxia
JOURNAL OF INFECTIOUS DISEASES
Rodriguez-Villodres, N; Gil-Marques, ML; Alvarez-Marin, R; Bonnin, RA; Pachon-Ibanez, ME; Aguilar-Guisado, M; Naas, T; Aznar, J; Pachon, J; Lepe, JA; Smani, Y
Extended-spectrum resistance to beta-lactams/beta-lactamase inhibitors (ESRI) evolved from low-level resistant Escherichia coli
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Milanes-Guisado, Y; Gutierrez-Valencia, A; Munoz-Pichardo, JM; Rivero, A; Trujillo-Rodriguez, M; Ruiz-Mateos, E; Espinosa, N; Roca-Oporto, C; Viciana, P; Lopez-Cortes, LF
Is immune recovery different depending on the use of integrase strand transfer inhibitor-, non-nucleoside reverse transcriptase- or boosted protease inhibitor-based regimens in antiretroviral-naive HIV-infected patients?
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Cardozo, C; Cuervo, G; Salavert, M; Merino, P; Gioia, F; Fernandez-Ruiz, M; Lopez-Cortes, LE; Escola-Verge, L; Montejo, M; Munoz, P; Aguilar-Guisado, M; Puerta-Alcalde, P; Tasias, M; Ruiz-Gaitan, A; Gonzalez, F; Puig-Asensio, M; Vena, A; Marco, F; Peman, J; Fortun, J; Aguado, JM; Almirante, B; Soriano, A; Carratala, J; Garcia-Vidal, C
An evidence-based bundle improves the quality of care and outcomes of patients with candidaemia
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Cornely, OA; Cisneros, JM; Torre-Cisneros, J; Rodriguez-Hernandez, MJ; Tallon-Aguilar, L; Calbo, E; Horcajada, JP; Queckenberg, C; Zettelmeyer, U; Arenz, D; Rosso-Fernandez, CM; Jimenez-Jorge, S; Turner, G; Raber, S; O'Brien, S; Luckey, A
Pharmacokinetics and safety of aztreonam/avibactam for the treatment of complicated intra-abdominal infections in hospitalized adults: results from the REJUVENATE study
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
Vitalle, J; Tarancon-Diez, L; Jimenez-Leon, MR; Terren, I; Orrantia, A; Roca-Oporto, C; Lopez-Cortes, L; Ruiz-Mateos, E; Zenarruzabeitia, O; Borrego, F
CD300a identifies a CD4(+)memory T cell subset with a higher susceptibility to HIV-1 infection
AIDS
De Pablo-Bernal, RS; Jimenez-Leon, MR; Tarancon-Diez, L; Gutierrez-Valencia, A; Serna-Gallego, A; Trujillo-Rodriguez, M; Alvarez-Rios, AI; Milanes-Guisado, Y; Espinosa, N; Roca-Oporto, C; Viciana, P; Lopez-Cortes, LF; Ruiz-Mateos, E
Modulation of Monocyte Activation and Function during Direct Antiviral Agent Treatment in Patients Coinfected with HIV and Hepatitis C Virus
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Gudiol, C; Arnan, M; Aguilar-Guisado, M; Royo-Cebrecos, C; Sanchez-Ortega, I; Montero, I; Martin-Gandul, C; Laporte-Amargis, J; Albasanz-Puig, A; Nicolae, S; Perayre, M; Berbel, D; Tebe, C; Riera, J; Sureda, A; Cisneros, JM; Carratala, J
A Randomized, Double-Blind, Placebo-Controlled Trial (TAURCAT Study) of Citrate Lock Solution for Prevention of Endoluminal Central Venous Catheter Infection in Neutropenic Hematological Patients
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Bassetti, M; Vena, A; Meroi, M; Cardozo, C; Cuervo, G; Giacobbe, DR; Salavert, M; Merino, P; Gioia, F; Fernandez-Ruiz, M; Lopez-Cortes, LE; Almirante, B; Escola-Verge, L; Montejo, M; Aguilar-Guisado, M; Puerta-Alcalde, P; Tasias, M; Ruiz-Gaitan, A; Gonzalez, F; Puig-Asensio, M; Marco, F; Peman, J; Fortun, J; Aguado, JM; Soriano, A; Carratala, J; Garcia-Vidal, C; Valerio, M; Sartor, A; Bouza, E; Munoz, P
Factors associated with the development of septic shock in patients with candidemia: a post hoc analysis from two prospective cohorts
CRITICAL CARE
Cordero, E; Bulnes-Ramos, A; Aguilar-Guisado, M; Escribano, FG; Olivas, I; Torre-Cisneros, J; Gavalda, J; Aydillo, T; Moreno, A; Montejo, M; Farinas, MC; Carratala, J; Munoz, P; Blanes, M; Fortun, J; Suarez-Benjumea, A; Lopez-Medrano, F; Roca, C; Lara, R; Perez-Romero, P
Effect of Influenza Vaccination Inducing Antibody Mediated Rejection in Solid Organ Transplant Recipients
FRONTIERS IN IMMUNOLOGY
Dominguez, AV; Algaba, RA; Canturri, AM; Villodres, AR; Smani, Y
Antibacterial Activity of Colloidal Silver against Gram-Negative and Gram-Positive Bacteria
ANTIBIOTICS-BASEL
Guisado-Gil, AB; Infante-Dominguez, C; Penalva, G; Praena, J; Roca, C; Navarro-Amuedo, MD; Aguilar-Guisado, M; Espinosa-Aguilera, N; Poyato-Borrego, M; Romero-Rodriguez, N; Aldabo, T; Salto-Alejandre, S; de Pipaon, MRP; Lepe, JA; Martin-Gutierrez, G; Gil-Navarro, MV; Molina, J; Pachon, J; Cisneros, JM
Impact of the COVID-19 Pandemic on Antimicrobial Consumption and Hospital-Acquired Candidemia and Multidrug-Resistant Bloodstream Infections
ANTIBIOTICS-BASEL
Herrera-Espejo, S; Cebrero-Cangueiro, T; Labrador-Herrera, G; Pachon, J; Pachon-Ibanez, ME; Alvarez-Marin, R
In Vitro Activity of Pentamidine Alone and in Combination with Antibiotics against Multidrug-Resistant Clinical Pseudomonas aeruginosa Strains
ANTIBIOTICS-BASEL
Pech-Puch, D; Berastegui-Cabrera, J; Perez-Povedano, M; Villegas-Hernandez, H; Guillen-Hernandez, S; Cautain, B; Reyes, F; Pachon, J; Gomez, P; Rodriguez, J; Jimenez, C; Sanchez-Cespedes, J
Antiviral and Antiproliferative Potential of Marine Organisms From the Yucatan Peninsula, Mexico
FRONTIERS IN MARINE SCIENCE
HIRZEL C, FERREIRA VH, L’HUILLIER AG, HOSCHLER K, CORDERO E, LIMAYE AP, ENGLUND JA, REID G, HUMAR A, KUMAR D, INFLUENZAIN TRANSPLANTSTUDY GROUP
HUMORAL RESPONSE TO NATURAL INFLUENZA INFECTION IN SOLID ORGAN TRANSPLANT RECIPIENTS.
AM J TRANSPLANT
PEREZ-NADALES E, GUTIERREZ-GUTIERREZ B, NATERA AM, ABDALA E, REINA MAGALHÃES M, MULARONI A, MONACO F, CAMERA PIERROTTI L, PINHEIRO FREIRE M, IYER RN, MEHTA STEINKE S, GRAZIA CALVI E, TUMBARELLO M, FALCONE M, FERNANDEZ-RUIZ M, MARIA COSTA-MATEO J, RANA MM, MARA VAREJÃO STRABELLI T, PAUL M, CARMEN FARIÑAS M, CLEMENTE WT, ROILIDESE, MUÑOZ P, DEWISPELAEREL, LOECHES B, LOWMAN W, HOCK TAN B, ESCUDERO-SANCHEZ R, BODRO M, ANTONIO GROSSI P, SOLDANI F, GUNSEREN F, NESTOROVA N, PASCUAL A, MARTINEZ-MARTINEZ L, AGUADO JM, RODRIGUEZ-BAÑO J, TORRE-CISNEROSJ, REIPI/INCREMENT-SOT INVESTIGATORS
PREDICTORS OF MORTALITY IN SOLID ORGAN TRANSPLANT RECIPIENTS WITH BLOODSTREAM INFECTIONS DUE TO CARBAPENEMASE-PRODUCING ENTEROBACTERALES: THE IMPACT OF CYTOMEGALOVIRUS DISEASE AND LYMPHOPENIA
AM J TRANSPLANT
CISNEROS JM, ROSSO-FERNANDEZ CM, ROCA-OPORTO C, DE PASCALE G, JIMENEZ-JORGE S, FERNANDEZ-HINOJOSA E, MATTHAIOU DK, RAMIREZ P, DIAZ-MIGUEL RO, ESTELLA A, ANTONELLI M, DIMOPOULOS G, GARNACHO-MONTERO J, MAGIC BULLET WORKING GROUP WP1
COLISTIN VERSUS MEROPENEM IN THE EMPIRICAL TREATMENT OF VENTILATOR-ASSOCIATED PNEUMONIA (MAGIC BULLET STUDY): AN INVESTIGATOR-DRIVEN, OPEN-LABEL, RANDOMIZED, NONINFERIORITY CONTROLLED TRIAL
CRIT CARE.
MOLINA-ORTEGA A, MARTIN-GANDUL C, MENA-ROMO JD, RODRIGUEZ-HERNANDEZ MJ, SUÑER M, BERNAL C,SANCHEZ M,SANCHEZ-CESPEDESJ, PEREZ ROMERO P, CORDERO E
IMPACT OF PRETRANSPLANT CMV-SPECIFIC T-CELL IMMUNE RESPONSE IN THE CONTROL OF CMV INFECTION AFTER SOLID ORGAN TRANSPLANTATION: A PROSPECTIVE COHORT STUDY
CLIN MICROBIOL INFECT. 2
RODRIGUEZ-VILLODRES A, BONNIN RA, ORTIZ DE LA ROSA JM, ALVAREZ-MARIN R, NAAS T, AZNAR J, PACHON J, LEPEJA,SMANI
PHYLOGENY, RESISTOME, AND VIRULOME OF ESCHERICHIA COLI CAUSING BILIARY TRACT INFECTIONS.
J CLIN MED.
MOLINA J, NOGUER M, LEPE JA, PEREZ-MORENO MA, AGUILAR-GUISADO M, LASSO DE LAVEGA R, PEÑALVA G, CRESPO-RIVASJC, GIL-NAVARRO MV,SALVADOR J, CISNEROSJM
CLINICAL IMPACT OF AN EDUCATIONAL ANTIMICROBIAL STEWARDSHIP PROGRAM ASSOCIATED WITH INFECTIOUS DISEASES CONSULTATION TARGETING PATIENTS WITH CANCER: RESULTS OF A 9-YEAR QUASI-EXPERIMENTAL STUDY WITH AN INTERRUPTED TIME-SERIES ANALYSIS.
J INFECT
L’HUILLIER AG, FERREIRA VH, HIRZEL C, CORDERO E, LIMAYE AP, REID G, ENGLUND J, BLUMBERG E, KUMAR D, HUMAR A
CYTOKINE PROFILES AND SEVERITY OF INFLUENZA INFECTION IN TRANSPLANT RECIPIENTS.
J INFECT DIS.
MANGASEL, RUBIO A,ALVAREZ-MARIN R,LABRADOR-HERRERA G, PACHON J, PACHON-IBAÑEZ ME, DIVINAF, PEREZ-PULIDO AJ
PANGENOME OF ACINETOBACTER BAUMANNII UNCOVERS TWO GROUPS OF GENOMES, ONE OF THEM WITH GENES INVOLVED IN CRISPR/CAS DEFENCE SYSTEMS ASSOCIATED WITH THE ABSENCE OF PLASMIDSAND EXCLUSIVE GENESFOR BIOFILM FORMATION.
MICROB GENOM
AYERBE-ALGABA R, GIL-MARQUESML,MIRO-CANTURRIA, PARRA-MILLAN R, PACHON-IBAÑEZ ME, JIMENEZ-MEJIAS ME, PACHON J,S
THE ANTHELMINTIC OXYCLOZANIDE RESTORES THE ACTIVITY OF COLISTIN AGAINST COLISTIN-RESISTANT GRAM-NEGATIVE BACILLI.
INT J ANTIMICROB AGENTS.
MIRO-CANTURRIA,AYERBE-ALGABA R,SMANI
DRUG REPURPOSING FOR THE TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS.
FRONT MICROBIOL.
JIMENEZ-GONZALEZ V, OGALLA-GARCIA E, GARCIA-QUINTANILLA M, GARCIA-QUINTANILLA A
DECIPHERING GRINA/LIFEGUARD1: NUCLEAR LOCATION, CA2+ HOMEOSTASIS AND VESICLE TRANSPORT
INT J MOL SCI.
BLASCO L,AMBROAA, LOPEZ M, FERNANDEZ-GARCIAL, BLERIOT I, TRASTOY R, RAMOS-VIVASJ, COENYET,FERNANDEZ-CUENCAF,VILAJ,MARTINEZ-MARTINEZ L, RODRIGUEZ-BAÑO J, PASCUAL A, CISNEROS JM, PACHON J, BOU G, TOMAS M
COMBINED USE OF THE AB105-2ΦΔCI LYTIC MUTANT PHAGE AND DIFFERENT ANTIBIOTICS IN CLINICAL ISOLATES OF MULTI-RESISTANT ACINETOBACTER BAUMANNII.
MICROORGANISMS
MARRUGAL-LORENZO JA, SERNA-GALLEGO A, BERASTEGUI-CABRERA J, PACHON J, SANCHEZ-CESPEDESJ
REPOSITIONING SALICYLANILIDE ANTHELMINTIC DRUGS TO TREAT ADENOVIRUS INFECTIONS.
SCI REP.
GONZALEZ I, MOLINA-ORTEGAA, PEREZ-ROMERO P,ECHEVARRIAJE, HEL, TARRAGO D
VARICELLA-ZOSTER VIRUS CLADES CIRCULATING IN SPAIN OVER TWO DECADES.
J CLIN VIROL.
OPEZ-CORTESLE,AYERBE-GARCIA R, CARRASCO-HERNANDEZ L,FRAILE-RAMOSE, CARMONA-CABALLERO JM, QUINTANA-GALLEGO E, VALIDO-MORALES A, PRAENA J, PACHON-DIAZ J, DOMUS OPAT GROUP
OUTPATIENT PARENTERAL ANTIMICROBIAL TREATMENT FOR NON-CYSTIC FIBROSIS BRONCHIECTASIS EXACERBATIONS: A PROSPECTIVE MULTICENTRE OBSERVATIONAL COHORT STUDY.
RESPIRATION.
MITSUWAN W, JIMENEZ-MUNGUIA I, VISUTTHI M, SIANGLUM W, REIPI/GEIH STUDY GROUP, RODRIGUEZ-ORTEGA MJ,VORAVUTHIKUNCHAISP
RHODOMYRTONE DECREASES STAPHYLOCOCCUS AUREUS SIGB ACTIVITY DURING EXPONENTIALLY GROWING PHASE AND INHIBITS HAEMOLYTIC ACTIVITY WITHIN MEMBRANE VESICLES.
MICROB PATHOG.
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Executive summary of clinical practice guideline for the management of invasive diseases caused by Aspergillus: 2018 Update by the GEMICOMED-SEIMC/REIPI
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Infect Immun
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Multinational case-control study of risk factors for the development of late invasive pulmonary aspergillosis following kidney transplantation.
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Transpl Infect Dis
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